Orr Ashenberg
Affiliations: | Fred Hutch Cancer Research Center |
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Parents
Sign in to add mentor| Amy E. Keating | grad student | MIT | |
| Michael T. Laub | grad student | MIT | |
| Jeese Bloom | post-doc | Fred Hutch Cancer Research Center |
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Publications
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| Hwang WL, Jagadeesh K, Guo J, et al. (2020) Single-nucleus RNA-seq of frozen archival primary pancreatic ductal adenocarcinoma uncovers multi-compartment intratumoral heterogeneity associated with neoadjuvant treatment. Journal of Clinical Oncology. 38: 4633-4633 |
| Cohen O, Abravanel D, Slyper M, et al. (2020) Abstract GS6-05: A joint atlas of single-cell and bulk RNA-seq in metastatic breast cancer allows inference of oncogenic and drug-resistant transcriptional programs in malignant cells and the tumor microenvironment Cancer Research. 80 |
| Jerby L, Shah P, Cuoco MS, et al. (2019) Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance Cancer Immunology Research. 7 |
| Hwang WL, Jagadeesh KA, Ashenberg O, et al. (2019) Abstract A22: Molecular subtypes and resistance programs in pancreatic ductal adenocarcinoma elucidated with single-nucleus RNA-seq Cancer Research. 79 |
| Phillips AM, Ponomarenko AI, Chen K, et al. (2018) Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. Plos Biology. 16: e3000008 |
| Ashenberg O, Padmakumar J, Doud MB, et al. (2017) Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA. Plos Pathogens. 13: e1006288 |
| Doud MB, Ashenberg O, Bloom JD. (2015) Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs. Molecular Biology and Evolution. 32: 2944-60 |
| Ashenberg O, Gong LI, Bloom JD. (2013) Mutational effects on stability are largely conserved during protein evolution. Proceedings of the National Academy of Sciences of the United States of America. 110: 21071-6 |
| Reinke AW, Baek J, Ashenberg O, et al. (2013) Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Science (New York, N.Y.). 340: 730-4 |
| Ashenberg O, Laub MT. (2013) Using analyses of amino acid coevolution to understand protein structure and function Methods in Enzymology. 523: 191-212 |