Isaac J. Krauss, Ph.D.
Affiliations: | Chemistry | Brandeis University, Waltham, MA, United States |
Area:
Organic Synthesis, Chemical Biology, Glycobiology, Transition-metal-catalyzed reactionsWebsite:
http://www.brandeis.edu/facultyguide/person.html?emplid=26a07b969be48a785fa1a951170fd8e3886a1dc3Google:
"Isaac J. Krauss"Mean distance: 7.46 | S | N | B | C | P |
Parents
Sign in to add mentorBarry M. Trost | research assistant | 1998 | Stanford | |
James L. Leighton | grad student | 2003 | Columbia | |
(Highly regioselective diastereoselective directed hydroformylation of allyl ethers ; Highly practical and enantioselective ligands for Cu-catalyzed conjugate addition) | ||||
Samuel J. Danishefsky | post-doc | 2003-2008 | Memorial Sloan-Kettering Cancer Center |
Children
Sign in to add traineeJ Sebastian Temme | grad student | ||
Anurag Roy | grad student | 2021- | Brandeis |
Wenbo Pei | grad student | 2014 | Brandeis |
MAHESH NERALKAR | post-doc | 2019- | Brandeis |
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Publications
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Neralkar M, Xu B, Horiya S, et al. (2022) Large-Scale Synthesis of ManGlcNAc High-Mannose Glycan and the Effect of the Glycan Core on Multivalent Recognition by HIV Antibody 2G12. Acs Infectious Diseases. 8: 2232-2241 |
Redman RL, Krauss IJ. (2021) Directed Evolution of 2'-Fluoro-Modified, RNA-Supported Carbohydrate Clusters That Bind Tightly to HIV Antibody 2G12. Journal of the American Chemical Society. 143: 8565-8571 |
Neralkar M, Tian L, Redman RL, et al. (2021) Synthesis of Mannosidase-Stable Man and Man Glycans Containing S-linked Manα1→2Man Termini. Organic Letters |
Matos JO, Kumar RP, Ma AC, et al. (2020) Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase. Biochemistry |
Nguyen DN, Redman RL, Horiya S, et al. (2020) The impact of sustained immunization regimens on the antibody response to oligomannose glycans. Acs Chemical Biology |
Morehouse BR, Kumar RP, Matos JO, et al. (2019) Direct evidence for an enzyme generated LPP intermediate in (+)-limonene synthase using a fluorinated GPP substrate analog. Acs Chemical Biology |
Nguyen DN, Xu B, Stanfield RL, et al. (2019) Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities. Acs Central Science. 5: 237-249 |
Tian L, Krauss IJ. (2018) Stereoselective Homocrotylation of Aldehydes: Enantioselective Synthesis of Allylic-Substituted Z/ E-Alkenes. Organic Letters |
Stanfield RL, Nguyen DN, Krauss IJ, et al. (2018) Synthetic glycopeptide selected by directed evolution in complex with anti-HIV-1 Fab 2G12 Acta Crystallographica Section a Foundations and Advances. 74: a178-a178 |
Horiya S, Bailey JK, Krauss IJ. (2017) Directed Evolution of Glycopeptides Using mRNA Display. Methods in Enzymology. 597: 83-141 |