Zephan Melville
Affiliations: | 2012-2017 | Biochemistry and Molecular Biology | University of Maryland School of Medicine, Baltimore, MD, United States |
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Sign in to add mentor| David J. Weber | grad student | 2012-2017 | University of Maryland Medical School |
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| Melville Z, Dridi H, Yuan Q, et al. (2022) A drug and ATP binding site in type 1 ryanodine receptor. Structure (London, England : 1993) |
| Yuan Q, Dridi H, Clarke OB, et al. (2021) RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation. Acta Neuropathologica Communications. 9: 186 |
| Dridi H, Kushnir A, Zalk R, et al. (2020) Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target. Nature Reviews. Cardiology |
| Hernández-Ochoa EO, Melville Z, Vanegas C, et al. (2018) Loss of S100A1 expression leads to Ca release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1. Physiological Reports. 6: e13822 |
| Melville Z, Hernandez-Ochoa EO, Pratt SJ, et al. (2017) The activation of PKA by the calcium-binding protein S100A1 is independent of cyclic AMP. Biochemistry |
| Melville Z, Aligholizadeh E, McKnight LE, et al. (2017) X-ray crystal structure of human calcium-bound S100A1. Acta Crystallographica. Section F, Structural Biology Communications. 73: 215-221 |
| Coburn K, Melville Z, Aligholizadeh E, et al. (2017) Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallographica. Section F, Structural Biology Communications. 73: 209-214 |
| Cavalier MC, Melville Z, Aligholizadeh E, et al. (2016) Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography. Acta Crystallographica. Section D, Structural Biology. 72: 753-760 |
| Melville Z, Varney K, Cavalier M, et al. (2015) Characterizing a New Metal Binding Site in S100B Biophysical Journal. 108: 48a |