Robert E. Hughes

Affiliations: 
Buck Institute for Research on Aging 
Area:
Neurodegeneration, Aging
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"Robert Hughes"
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Publications

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Peters TW, Nelson CS, Gerencser AA, et al. (2018) Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation. G3 (Bethesda, Md.)
Lucanic M, Garrett T, Yu I, et al. (2016) Chemical activation of a food deprivation signal extends lifespan. Aging Cell
Peters TW, Miller AW, Tourette C, et al. (2015) Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae. G3 (Bethesda, Md.)
Agrawal P, Reynolds J, Chew S, et al. (2014) DEPTOR is a stemness factor that regulates pluripotency of embryonic stem cells. The Journal of Biological Chemistry. 289: 31818-26
Orr AL, Ashok D, Sarantos MR, et al. (2014) Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. Plos One. 9: e89938
Tourette C, Li B, Bell R, et al. (2014) A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease. The Journal of Biological Chemistry. 289: 6709-26
Orr AL, Ashok D, Sarantos MR, et al. (2013) Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. Free Radical Biology & Medicine. 65: 1047-59
Sarantos MR, Papanikolaou T, Ellerby LM, et al. (2012) Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington's Disease. Journal of Huntington's Disease. 1: 195-210
Miller JP, Yates BE, Al-Ramahi I, et al. (2012) A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease. Plos Genetics. 8: e1003042
Peters TW, Rardin MJ, Czerwieniec G, et al. (2012) Tor1 regulates protein solubility in Saccharomyces cerevisiae. Molecular Biology of the Cell. 23: 4679-88
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