Christian A. Olsen

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2007-2010 Department of Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"Christian Olsen"
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Bolding JE, Martin-Gago P, Rajabi N, et al. (2022) Aryl Fluorosulfate Based Inhibitors that Covalently Target the SIRT5 Lysine Deacylase. Angewandte Chemie (International Ed. in English)
Moreno-Yruela C, Olsen CA. (2022) Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. Acs Medicinal Chemistry Letters. 13: 779-785
Moreno-Yruela C, Bæk M, Monda F, et al. (2022) Chiral Posttranslational Modification to Lysine ε-Amino Groups. Accounts of Chemical Research
Rajabi N, Hansen TN, Nielsen AL, et al. (2022) Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme. Angewandte Chemie (International Ed. in English). e202115805
Moreno-Yruela C, Zhang D, Wei W, et al. (2022) Class I histone deacetylases (HDAC1-3) are histone lysine delactylases. Science Advances. 8: eabi6696
Troelsen KS, Bæk M, Nielsen AL, et al. (2021) Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase. Rsc Chemical Biology. 2: 627-635
Nielsen AL, Rajabi N, Kudo N, et al. (2021) Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration. Rsc Chemical Biology. 2: 612-626
Moreno-Yruela C, Olsen CA. (2021) High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays. Star Protocols. 2: 100313
Moreno-Yruela C, Bæk M, Vrsanova AE, et al. (2021) Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases. Nature Communications. 12: 62
Troelsen KS, Bæk M, Nielsen AL, et al. (2021) Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase Rsc Chemical Biology. 2: 627-635
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