Christian A. Olsen

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2007-2010 Department of Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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Nielsen AL, Olsen CA. (2020) Finding the gas pedal on a slow sirtuin. The Journal of Biological Chemistry. 295: 1400-1401
Kitir B, Maolanon AR, Ohm RG, et al. (2017) Chemical Editing of Macrocyclic Natural Products Provides HDAC Inhibitors with Picomolar Affinities. Biochemistry
Lai JI, Leman LJ, Ku S, et al. (2017) Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters
Maolanon AR, Kristensen HM, Leman LJ, et al. (2016) Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes. Chembiochem : a European Journal of Chemical Biology
Maolanon AR, Madsen AS, Olsen CA. (2016) Innovative Strategies for Selective Inhibition of Histone Deacetylases. Cell Chemical Biology. 23: 759-768
Madsen AS, Andersen C, Daoud M, et al. (2016) Investigating the Sensitivity of NAD+-Dependent Sirtuin Deacylation Activities to NADH. The Journal of Biological Chemistry
Baldry M, Kitir B, Frøkiær H, et al. (2016) The agr Inhibitors Solonamide B and Analogues Alter Immune Responses to Staphylococccus aureus but Do Not Exhibit Adverse Effects on Immune Cell Functions. Plos One. 11: e0145618
Madsen AS, Olsen CA. (2016) A potent trifluoromethyl ketone histone deacetylase inhibitor exhibits class-dependent mechanism of action Medchemcomm. 7: 464-470
Madsen AS, Olsen CA. (2016) Optoepigenetics: An acetylation photoswitch Nature Chemical Biology
Galleano I, Schiedel M, Jung M, et al. (2016) A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation Journal of Medicinal Chemistry. 59: 1021-1031
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