Russell A Miller
Affiliations: | Biochemistry | University of Wisconsin, Madison, Madison, WI |
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| Bollinger E, Siddall CP, Greizer T, et al. (2019) 1922-P: Branched-Chain Ketoacid Dehydrogenase Kinase Inhibition Acutely Improves Glycemia and Alters the Response to Feeding in Mice Diabetes. 68 |
| Ryder T, Calabrese MF, Walker GS, et al. (2018) Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-activated Protein Kinase (AMPK). Journal of Medicinal Chemistry |
| Miller RA, Shi Y, Lu W, et al. (2018) Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nature Medicine |
| Cokorinos EC, Delmore J, Reyes AR, et al. (2017) Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metabolism. 25: 1147-1159.e10 |
| Salatto CT, Miller RA, Cameron KO, et al. (2017) Selective Activation of AMPK b1-containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy. The Journal of Pharmacology and Experimental Therapeutics |
| Cameron KO, Kung DW, Kalgutkar AS, et al. (2016) Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. Journal of Medicinal Chemistry |
| Calabrese MF, Rajamohan F, Harris MS, et al. (2014) Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. Structure (London, England : 1993). 22: 1161-72 |
| Miller RA, Chu Q, Xie J, et al. (2013) Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature. 494: 256-60 |
| Miller RA, Chu Q, Le Lay J, et al. (2011) Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. The Journal of Clinical Investigation. 121: 2518-28 |
| Holland WL, Miller RA, Wang ZV, et al. (2011) Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nature Medicine. 17: 55-63 |