John H. Exton

Physiology Vanderbilt University, Nashville, TN 
the mechanisms by which growth factors and hormones control cell functions
"John H. Exton"

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Norman Edson grad student 1963 University of Otago
 (Relationships between carbohydrate and fat metabolism : ketone body formation by isolated rat-liver cells)
Charles Rawlinson Rollo Park post-doc
Earl W. Sutherland post-doc Vanderbilt
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Exton JH. (2011) Glucagon Signal-Transduction Mechanisms Comprehensive Physiology. 435-450
Exton JH. (2011) Phospholipid‐Derived Second Messengers Comprehensive Physiology. 255-291
Brown HA, Henage LG, Preininger AM, et al. (2007) Biochemical Analysis of Phospholipase D Methods in Enzymology. 434: 49-87
Hu P, Han Z, Couvillon AD, et al. (2006) Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression Molecular and Cellular Biology. 26: 3071-3084
Shin OH, Exton JH. (2006) Assays and properties of arfaptin 2 binding to Rac1 and ADP-ribosylation factors (Arfs) Methods in Enzymology. 404: 359-367
Henage LG, Exton JH, Brown HA. (2006) Kinetic analysis of a mammalian phospholipase D: Allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides Journal of Biological Chemistry. 281: 3408-3417
Couvillon AD, Exton JH. (2006) Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells Cellular Signalling. 18: 715-728
Chen JS, Exton JH. (2005) Sites on phospholipase D2 phosphorylated by PKCα Biochemical and Biophysical Research Communications. 333: 1322-1326
Hu T, Exton JH. (2005) A point mutation at phenylalanine 663 abolishes protein kinase Cα's ability to translocate to the perinuclear region and activate phospholipase D1 Biochemical and Biophysical Research Communications. 333: 750-753
Kook S, Exton JH. (2005) Identification of interaction sites of protein kinase Cα on phospholipase D1 Cellular Signalling. 17: 1423-1432
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