Bruce Furie

Harvard - BIDMC 
hemostasis and thrombosis
"Bruce Furie"
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Schulman S, El-Darzi E, Florido MH, et al. (2020) A coagulation defect arising from heterozygous premature termination of tissue factor. The Journal of Clinical Investigation
Eriksson O, Stopa J, Furie B. (2019) Identification of PDI Substrates by Mechanism-Based Kinetic Trapping. Methods in Molecular Biology (Clifton, N.J.). 1967: 165-182
Eriksson O, Chiu J, Hogg PJ, et al. (2019) Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. The Journal of Biological Chemistry
Zwicker JI, Schlechter BL, Stopa JD, et al. (2019) Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer. Jci Insight
Bekendam RH, Iyu D, Passam F, et al. (2018) Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. Journal of Thrombosis and Haemostasis : Jth
Sharda A, Furie B. (2018) Regulatory role of thiol isomerases in thrombus formation. Expert Review of Hematology. 11: 437-448
Zwicker JI, Schlechter BL, Stopa JD, et al. (2018) Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study) Blood. 132: 985-985
Peng S, Xue G, Gong L, et al. (2017) A long-acting PAI-1 inhibitor reduce thrombus formation. Thrombosis and Haemostasis
Stopa JD, Baker KM, Grover SP, et al. (2017) Kinetic-based Trapping by Intervening Sequence Variants of the Active Sites of Protein Disulfide Isomerase Identifies Platelet Protein Substrates. The Journal of Biological Chemistry
Bowley SR, Fang C, Merrill-Skoloff G, et al. (2017) Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation. Nature Communications. 8: 14151
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