Sneha Saxena
Affiliations: | Biochemistry | Indian Institute of Science Bangalore |
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Parents
Sign in to add mentor| Ganesh Nagaraju | grad student | IISc Bangalore | |
| Lee Zou | post-doc | MGH Harvard Medical School |
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Publications
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| Kawale AS, Ran X, Patel PS, et al. (2024) APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science Advances. 10: eadk2771 |
| Wang M, Ran X, Leung W, et al. (2023) ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy. Genes & Development |
| Leung W, Simoneau A, Saxena S, et al. (2023) ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms. Cell Reports. 42: 112792 |
| Saxena S, Zou L. (2022) Hallmarks of DNA replication stress. Molecular Cell. 82: 2298-2314 |
| Genois MM, Gagné JP, Yasuhara T, et al. (2020) CARM1 regulates replication fork speed and stress response by stimulating PARP1. Molecular Cell |
| Somyajit K, Saxena S, Babu S, et al. (2020) Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart. Nucleic Acids Research |
| Saxena S, Dixit S, Somyajit K, et al. (2019) ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response. Cell Reports. 29: 551-559.e4 |
| Saxena S, Somyajit K, Nagaraju G. (2018) XRCC2 Regulates Replication Fork Progression during dNTP Alterations. Cell Reports. 25: 3273-3282.e6 |
| Mishra A, Saxena S, Kaushal A, et al. (2017) RAD51C/XRCC3 facilitates mitochondrial DNA replication and maintains integrity of the mitochondrial genome. Molecular and Cellular Biology |
| Somyajit K, Banik B, Saxena S, et al. (2016) Trans-dichlorooxovandium (IV) complex as a novel photoinducible DNA interstrand crosslinker for cancer therapy. Carcinogenesis. 37: 145-56 |