Sneha Saxena

Biochemistry Indian Institute of Science Bangalore 
"Sneha Saxena"
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Saxena S, Nabel CS, Seay TW, et al. (2024) Unprocessed genomic uracil as a source of DNA replication stress in cancer cells. Molecular Cell
Kawale AS, Ran X, Patel PS, et al. (2024) APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science Advances. 10: eadk2771
Wang M, Ran X, Leung W, et al. (2023) ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy. Genes & Development
Leung W, Simoneau A, Saxena S, et al. (2023) ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms. Cell Reports. 42: 112792
Saxena S, Zou L. (2022) Hallmarks of DNA replication stress. Molecular Cell. 82: 2298-2314
Genois MM, Gagné JP, Yasuhara T, et al. (2020) CARM1 regulates replication fork speed and stress response by stimulating PARP1. Molecular Cell
Somyajit K, Saxena S, Babu S, et al. (2020) Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart. Nucleic Acids Research
Saxena S, Dixit S, Somyajit K, et al. (2019) ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response. Cell Reports. 29: 551-559.e4
Saxena S, Somyajit K, Nagaraju G. (2018) XRCC2 Regulates Replication Fork Progression during dNTP Alterations. Cell Reports. 25: 3273-3282.e6
Mishra A, Saxena S, Kaushal A, et al. (2017) RAD51C/XRCC3 facilitates mitochondrial DNA replication and maintains integrity of the mitochondrial genome. Molecular and Cellular Biology
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