Robert E. MacKenzie
Affiliations: | McGill University, Montreal, QC, Canada |
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"Robert MacKenzie"Mean distance: 9.07
Children
Sign in to add trainee| Joelle N. Pelletier | grad student | 1995 | McGill |
| Erminia Di Pietro | grad student | 2004 | McGill |
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Publications
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| Christensen KE, Deng L, Leung KY, et al. (2013) A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development Human Molecular Genetics. 22: 3705-3719 |
| Christensen KE, Rohlicek CV, Andelfinger GU, et al. (2009) The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects. Human Mutation. 30: 212-20 |
| Christensen KE, MacKenzie RE. (2008) Chapter 14 Mitochondrial Methylenetetrahydrofolate Dehydrogenase, Methenyltetrahydrofolate Cyclohydrolase, and Formyltetrahydrofolate Synthetases Vitamins and Hormones. 79: 393-410 |
| Christensen KE, MacKenzie RE. (2006) Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals Bioessays. 28: 595-605 |
| Patel H, Di Pietro E, Mejia N, et al. (2005) NAD- and NADP-dependent mitochondrially targeted methylenetetrahydrofolate dehydrogenase-cyclohydrolases can rescue mthfd2 null fibroblasts Archives of Biochemistry and Biophysics. 442: 133-139 |
| Christensen KE, Mirza IA, Berghuis AM, et al. (2005) Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase Journal of Biological Chemistry. 280: 34316-34323 |
| Christensen KE, Patel H, Kuzmanov U, et al. (2005) Disruption of the Mthfd1 gene reveals a monofunctional 10- formyltetrahydrofolate synthetase in mammalian mitochondria Journal of Biological Chemistry. 280: 7597-7602 |
| Di Pietro E, Wang XL, MacKenzie RE. (2004) The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth Biochimica Et Biophysica Acta - General Subjects. 1674: 78-84 |
| Baggott JE, MacKenzie RE. (2003) 5,10-Methenyltetrahydrofolate cyclohydrolase, rat liver and chemically catalysed formation of 5-formyltetrahydrofolate Biochemical Journal. 374: 773-778 |
| Patel H, Di Pietro E, MacKenzie RE. (2003) Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs Journal of Biological Chemistry. 278: 19436-19441 |