Roberto A. Chica, Ph.D.

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 
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"Roberto Chica"
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Publications

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Rakotoharisoa RV, Seifinoferest B, Zarifi N, et al. (2023) Design of efficient artificial enzymes using crystallographically-enhanced conformational sampling. Biorxiv : the Preprint Server For Biology
St-Jacques AD, Rodriguez JM, Eason MG, et al. (2023) Computational remodeling of an enzyme conformational landscape for altered substrate selectivity. Nature Communications. 14: 6058
Chica RA. (2020) Protein Engineering, Design and Selection. Protein Engineering, Design & Selection : Peds. 33
Broom A, Rakotoharisoa RV, Thompson MC, et al. (2020) Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nature Communications. 11: 4808
Wang CY, Chang PM, Ary ML, et al. (2019) ProtaBank: A repository for protein design and engineering data. Protein Science : a Publication of the Protein Society. 28: 672
Damry AM, Mayer MM, Goto NK, et al. (2019) Solution NMR Structure of DANCER3-F34A, a rigid and natively folded single mutant of the dynamic protein DANCER-3 Journal of Back and Musculoskeletal Rehabilitation
St-Jacques AD, Eyahpaise MC, Chica RA. (2019) Computational Design of Multisubstrate Enzyme Specificity Acs Catalysis. 9: 5480-5485
Walton CJ, Thiebaut F, Brunzelle JS, et al. (2018) Structural determinants of the stereo-inverting activity of Pseudomonas stutzeri D-phenylglycine aminotransferase. Biochemistry
Wang CY, Chang PM, Ary ML, et al. (2018) ProtaBank: A repository for protein design and engineering data. Protein Science : a Publication of the Protein Society
Davey JA, Damry AM, Goto NK, et al. (2017) Rational design of proteins that exchange on functional timescales. Nature Chemical Biology
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