Alan M. Weiner, Ph.D.
|Biochemistry||University of Washington, Seattle, Seattle, WA|
Area:the origin of life
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|Pavelitz T, Gray LT, Padilla SL, et al. (2013) PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans. Mobile Dna. 4: 23|
|Weiner AM, Gray LT. (2013) What role (if any) does the highly conserved CSB-PGBD3 fusion protein play in Cockayne syndrome? Mechanisms of Ageing and Development. 134: 225-33|
|Gray LT, Fong KK, Pavelitz T, et al. (2012) Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans. Plos Genetics. 8: e1002972|
|Bailey AD, Gray LT, Pavelitz T, et al. (2012) The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells. Dna Repair. 11: 488-501|
|Gray LT, Weiner AM. (2010) Ubiquitin recognition by the Cockayne syndrome group B protein: binding will set you free. Molecular Cell. 38: 621-2|
|Cho HD, Sood VD, Baker D, et al. (2008) On the role of a conserved, potentially helix-breaking residue in the tRNA-binding alpha-helix of archaeal CCA-adding enzymes. Rna (New York, N.Y.). 14: 1284-9|
|Pavelitz T, Bailey AD, Elco CP, et al. (2008) Human U2 snRNA genes exhibit a persistently open transcriptional state and promoter disassembly at metaphase. Molecular and Cellular Biology. 28: 3573-88|
|Newman JC, Bailey AD, Fan HY, et al. (2008) An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. Plos Genetics. 4: e1000031|
|Cho HD, Verlinde CL, Weiner AM. (2007) Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases. Proceedings of the National Academy of Sciences of the United States of America. 104: 54-9|
|Newman JC, Bailey AD, Weiner AM. (2006) Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling. Proceedings of the National Academy of Sciences of the United States of America. 103: 9613-8|