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Ira Pastan

Affiliations: 
National Institutes of Health, Bethesda, MD 
Area:
Molecular Biology
Website:
http://ccr.nci.nih.gov/staff/staff.asp?profileid=5782
Google:
"Ira Pastan"
Mean distance: 14.27 (cluster 32)
 
SNBCP
Cross-listing: Neurotree

Parents

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Earl R. Stadtman post-doc 1959-1961 NIH

Children

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Itai Benhar grad student
Benoit de Crombrugghe post-doc
John A. Hanover post-doc NIH (NCI)
Frederick R. Maxfield post-doc NIH
Kenneth Yamada post-doc NIH
Robert J. Lefkowitz post-doc 1968-1970 NIH
Harold Elliot Varmus research scientist 1968-1970 NIH (DevTree)
BETA: Related publications

Publications

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Mazor R, Pastan I. (2020) Immunogenicity of Immunotoxins Containing Exotoxin A: Causes, Consequences, and Mitigation. Frontiers in Immunology. 11: 1261
Inoue S, Tsunoda T, Riku M, et al. (2020) Diffuse mesothelin expression leads to worse prognosis through enhanced cellular proliferation in colorectal cancer. Oncology Letters. 19: 1741-1750
Liu XF, Wei J, Zhou Q, et al. (2020) Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proceedings of the National Academy of Sciences of the United States of America
Zheng Z, Okada R, Kobayashi H, et al. (2019) Site-specific PEGylation of anti-mesothelin recombinant immunotoxins increases half-life and anti-tumor activity. Molecular Cancer Therapeutics
Fleming BD, Urban DJ, Hall M, et al. (2019) The engineered anti-GPC3 immunotoxin, HN3-ABD-T20, produces regression in mouse liver cancer xenografts via prolonged serum retention. Hepatology (Baltimore, Md.)
Cerise A, Bera TK, Liu X, et al. (2019) Anti-Mesothelin Recombinant Immunotoxin Therapy for Colorectal Cancer. Clinical Colorectal Cancer
Bera TK, Liu W, Leshem J, et al. (2019) Generation of a Transgenic BALB/c Mouse Line With Selective Expression of Human Mesothelin in Thyroid Gland: Application in Mesothelin-targeted Immunotherapy. Journal of Immunotherapy (Hagerstown, Md. : 1997)
Leshem Y, Pastan I. (2019) Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation in Preclinical Models. Toxins. 11
Kreitman R, Gorelik D, Stetler-Stevenson M, et al. (2019) Abstract CN07-03: Recombinant immunotoxins for hematologic malignancies Molecular Cancer Therapeutics. 18
Ho M, Fleming BD, Greten TF, et al. (2019) Abstract CN07-02: Immunotoxins targeting GPC3 for liver cancer Molecular Cancer Therapeutics. 18
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