Saurja DasGupta

Affiliations: 
Harvard Medical School, Boston, MA, United States 
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Radakovic A, DasGupta S, Wright TH, et al. (2022) Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 119
Krochmal D, Shao Y, Li NS, et al. (2022) Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nature Chemical Biology
DasGupta S, Nykiel K, Piccirilli JA. (2021) The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. Rna (New York, N.Y.)
DasGupta S, Piccirilli JA. (2021) The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation. Accounts of Chemical Research
DasGupta S. (2020) Molecular crowding and RNA catalysis. Organic & Biomolecular Chemistry
Walton T, DasGupta S, Duzdevich D, et al. (2020) In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proceedings of the National Academy of Sciences of the United States of America
Hoshika S, Leal NA, Kim MJ, et al. (2019) Hachimoji DNA and RNA: A genetic system with eight building blocks. Science (New York, N.Y.). 363: 884-887
Koirala D, Shelke SA, Dupont M, et al. (2018) Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Research
DasGupta S, Suslov NB, Piccirilli JA. (2017) Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme. Journal of the American Chemical Society
Biondi E, Lane JD, Das D, et al. (2016) Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Research
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