Saurja DasGupta

Affiliations: 
2024- University of Notre Dame, Notre Dame, IN, United States 
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Cohen ZR, Ding D, Zhou L, et al. (2024) Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life. Pnas Nexus. 3: pgae084
DasGupta S, Zhang S, Szostak JW. (2023) Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly. Acs Central Science. 9: 1670-1678
DasGupta S, Zhang SJ, Smela MP, et al. (2023) RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells. Chemistry (Weinheim An Der Bergstrasse, Germany). e202301376
Radakovic A, DasGupta S, Wright TH, et al. (2022) Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 119
Krochmal D, Shao Y, Li NS, et al. (2022) Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nature Chemical Biology
DasGupta S, Nykiel K, Piccirilli JA. (2021) The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. Rna (New York, N.Y.)
DasGupta S, Piccirilli JA. (2021) The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation. Accounts of Chemical Research
DasGupta S. (2020) Molecular crowding and RNA catalysis. Organic & Biomolecular Chemistry
Walton T, DasGupta S, Duzdevich D, et al. (2020) In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proceedings of the National Academy of Sciences of the United States of America
Hoshika S, Leal NA, Kim MJ, et al. (2019) Hachimoji DNA and RNA: A genetic system with eight building blocks. Science (New York, N.Y.). 363: 884-887
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