Saurja DasGupta
Affiliations: | Harvard Medical School, Boston, MA, United States |
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Parents
Sign in to add mentorJoseph A. Piccirilli | grad student | 2013-2018 | Chicago |
Jack W. Szostak | post-doc | Harvard Medical School |
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Publications
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Radakovic A, DasGupta S, Wright TH, et al. (2022) Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America. 119 |
Krochmal D, Shao Y, Li NS, et al. (2022) Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nature Chemical Biology |
DasGupta S, Nykiel K, Piccirilli JA. (2021) The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. Rna (New York, N.Y.) |
DasGupta S, Piccirilli JA. (2021) The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation. Accounts of Chemical Research |
DasGupta S. (2020) Molecular crowding and RNA catalysis. Organic & Biomolecular Chemistry |
Walton T, DasGupta S, Duzdevich D, et al. (2020) In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proceedings of the National Academy of Sciences of the United States of America |
Hoshika S, Leal NA, Kim MJ, et al. (2019) Hachimoji DNA and RNA: A genetic system with eight building blocks. Science (New York, N.Y.). 363: 884-887 |
Koirala D, Shelke SA, Dupont M, et al. (2018) Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Research |
DasGupta S, Suslov NB, Piccirilli JA. (2017) Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme. Journal of the American Chemical Society |
Biondi E, Lane JD, Das D, et al. (2016) Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Research |