Alan R. Saltiel

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction
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"Alan Saltiel"
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Publications

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Wang L, Mazagova M, Pan C, et al. (2019) YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America
Gan X, Wilson MW, Beyett TS, et al. (2019) Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat and human microsomes. Journal of Labelled Compounds & Radiopharmaceuticals
Beyett TS, Gan X, Reilly SM, et al. (2018) Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorganic & Medicinal Chemistry
Kim JY, Garcia-Carbonell R, Yamachika S, et al. (2018) ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell
Beyett TS, Gan X, Reilly SM, et al. (2018) Carboxylic acid derivatives of amlexanox display enhanced potency towards TBK1 and IKKϵ and reveal mechanisms for selective inhibition. Molecular Pharmacology
Skorobogatko Y, Dragan M, Cordon C, et al. (2018) RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America
Ahmadian M, Liu S, Reilly SM, et al. (2018) ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Reports. 22: 2849-2859
Zhao P, Wong KI, Sun X, et al. (2018) TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 172: 731-743.e12
Ichikawa T, Kita M, Matsui TS, et al. (2017) Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Journal of Cell Science
Reilly SM, Saltiel AR. (2017) Adapting to obesity with adipose tissue inflammation. Nature Reviews. Endocrinology
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