Alan R. Saltiel

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction
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Publications

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Reilly SM, Hung CW, Ahmadian M, et al. (2020) Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nature Metabolism. 2: 620-634
Zhao P, Saltiel AR. (2020) From Overnutrition to Liver Injury: AMP-Activated Protein Kinase in Nonalcoholic Fatty Liver Diseases. The Journal of Biological Chemistry
Zhao P, Sun X, Chaggan C, et al. (2020) An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. Science (New York, N.Y.). 367: 652-660
Sun X, Seidman JS, Zhao P, et al. (2019) Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metabolism
Wang L, Mazagova M, Pan C, et al. (2019) YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America
Gan X, Wilson MW, Beyett TS, et al. (2019) Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat and human microsomes. Journal of Labelled Compounds & Radiopharmaceuticals
Beyett TS, Gan X, Reilly SM, et al. (2018) Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorganic & Medicinal Chemistry
Kim JY, Garcia-Carbonell R, Yamachika S, et al. (2018) ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell
Beyett TS, Gan X, Reilly SM, et al. (2018) Carboxylic acid derivatives of amlexanox display enhanced potency towards TBK1 and IKKϵ and reveal mechanisms for selective inhibition. Molecular Pharmacology
Skorobogatko Y, Dragan M, Cordon C, et al. (2018) RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America
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