Clint Tavares
Affiliations: | 2008-2015 | Medicinal Chemistry | University of Texas at Austin, Austin, Texas, U.S.A. |
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Publications
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Kaoud TS, Johnson WH, Ebelt ND, et al. (2019) Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo. Nature Communications. 10: 5232 |
Jose J, Tavares CDJ, Ebelt ND, et al. (2017) Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth. Acs Medicinal Chemistry Letters. 8: 1072-1076 |
Tavares CD, Giles DH, Stancu G, et al. (2016) Signal Integration at Elongation Factor 2 Kinase; the Roles of Calcium, Calmodulin and Ser-500 Phosphorylation. The Journal of Biological Chemistry |
Lee K, Alphonse S, Piserchio A, et al. (2016) Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin. Structure (London, England : 1993) |
Tavares CD, Devkota AK, Dalby KN, et al. (2016) Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening. Methods in Molecular Biology (Clifton, N.J.). 1360: 19-33 |
Kaoud TS, Xie X, Park J, et al. (2016) Abstract A17: TRPM7 kinase domain is involved in breast tumor cell metastasis Cancer Research. 76 |
Wang Q, Edupuganti R, Tavares CD, et al. (2015) Using docking and alchemical free energy approach to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis. Frontiers in Molecular Biosciences. 2: 9 |
Warthaka M, Adelmann CH, Kaoud TS, et al. (2015) Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine. Acs Medicinal Chemistry Letters. 6: 47-52 |
Kaoud TS, Xie X, Park J, et al. (2015) Abstract 3569: Inhibition of the TRPM7 kinase domain inhibits breast cancer cell migration and invasion and tumor metastasis Cancer Research. 75: 3569-3569 |
Edupuganti R, Wang Q, Tavares CD, et al. (2014) Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitors. Bioorganic & Medicinal Chemistry. 22: 4910-6 |