David Giles

2013-2018 Chemical Biology and Medicinal Chemistry University of Texas at Austin, Austin, Texas, U.S.A. 
"David Giles"
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Kevin Dalby grad student 2013-2018 UT Austin
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Crittenden CM, Novelli ET, Xu G, et al. (2020) Structural Evaluation of Protein/Metal Complexes via Native Electrospray Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society For Mass Spectrometry
Kumar EA, Giles D, Dalby K. (2020) AMPK can stimulate eEF2 phosphorylation without regulating its cognate kinase eEF2K The Faseb Journal. 34: 1-1
Piserchio A, Will N, Giles DH, et al. (2019) Solution Structure of the Carboxy-Terminal Tandem Repeat Domain of Eukaryotic Elongation Factor 2 Kinase and its Role in Substrate Recognition. Journal of Molecular Biology
Will N, Lee K, Hajredini F, et al. (2018) Structural Dynamics of the Activation of Elongation Factor 2 Kinase by Ca-Calmodulin. Journal of Molecular Biology
Tavares CD, Giles DH, Stancu G, et al. (2016) Signal Integration at Elongation Factor 2 Kinase; the Roles of Calcium, Calmodulin and Ser-500 Phosphorylation. The Journal of Biological Chemistry
Will N, Piserchio A, Snyder I, et al. (2016) Structure of the C-terminal Helical Repeat Domain of Eukaryotic Elongation Factor 2 Kinase. Biochemistry
Lee K, Alphonse S, Piserchio A, et al. (2016) Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin. Structure (London, England : 1993)
Giles DH, Crittenden CM, Brodbelt JS, et al. (2016) Abstract 193: Mechanism of the AMPK-dependent activation of eukaryotic elongation factor 2 kinase (eEF-2K) Cancer Research. 76: 193-193
Tavares CD, Ferguson SB, Giles DH, et al. (2014) The molecular mechanism of eukaryotic elongation factor 2 kinase activation. The Journal of Biological Chemistry. 289: 23901-16
Madsen JA, Xu H, Robinson MR, et al. (2013) High-throughput database search and large-scale negative polarity liquid chromatography-tandem mass spectrometry with ultraviolet photodissociation for complex proteomic samples. Molecular & Cellular Proteomics : McP. 12: 2604-14
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