Dhulfiqar Ali Abed
Affiliations: | 2018 | Rutgers University, New Brunswick, New Brunswick, NJ, United States |
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| Lee S, Ali AR, Abed DA, et al. (2023) Structural modification of C2-substituents on 1,4-bis(arylsulfonamido)benzene or naphthalene-N,N'-diacetic acid derivatives as potent inhibitors of the Keap1-Nrf2 protein-protein interaction. European Journal of Medicinal Chemistry. 265: 116104 |
| Abed DA, Ali AR, Lee S, et al. (2023) Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction. European Journal of Medicinal Chemistry. 252: 115302 |
| Lee S, Abed DA, Nguyen MU, et al. (2022) Structure-activity relationships of 1,4-bis(arylsulfonamido)-benzene or naphthalene-N,N'-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction. European Journal of Medicinal Chemistry. 237: 114380 |
| Abed DA, Lee S, Wen X, et al. (2021) Optimization of 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acids as inhibitors of Keap1-Nrf2 protein-protein interaction to suppress neuroinflammation. Bioorganic & Medicinal Chemistry. 44: 116300 |
| Lee S, Abed DA, Beamer LJ, et al. (2020) Development of a Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for the Inhibition of Keap1-Nrf2 Protein-Protein Interaction. Slas Discovery : Advancing Life Sciences R & D. 2472555220935816 |
| Abed DA, Lee S, Hu L. (2020) Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction. Bioorganic & Medicinal Chemistry. 115343 |
| Abed DA, Goldstein M, Albanyan H, et al. (2015) Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents. Acta Pharmaceutica Sinica. B. 5: 285-299 |