Sebastian Pomplun
Affiliations: | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
Bioorganic chemistry, combinatorial drug discovery, chemical biology,Google:
"Sebastian Pomplun"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Felix Hausch | grad student | MPI Psychiatry Munich | |
| Brad L. Pentelute | post-doc | MIT |
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Publications
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| Kolos JM, Pomplun S, Jung S, et al. (2021) Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chemical Science. 12: 14758-14765 |
| Pomplun S, Jbara M, Schissel CK, et al. (2021) Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription. Acs Central Science. 7: 1408-1418 |
| Jbara M, Pomplun S, Schissel CK, et al. (2021) Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents. Journal of the American Chemical Society |
| Pomplun S, Jbara M, Quartararo AJ, et al. (2021) Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein. Acs Central Science. 7: 156-163 |
| Pomplun S. (2021) Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides Rsc Medicinal Chemistry. 12: 197-202 |
| Pomplun S. (2020) Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides. Rsc Medicinal Chemistry. 12: 197-202 |
| Pomplun S, Gates ZP, Zhang G, et al. (2020) Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries. Journal of the American Chemical Society. 142: 19642-19651 |
| Pomplun S, Shugrue CR, Schmitt AM, et al. (2020) Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release. Angewandte Chemie (International Ed. in English). 59: 11566-11572 |
| Pomplun S, Mohamed MY, Oelschlaegel T, et al. (2019) Efficient Pictet Spengler Bioconjugation with N-Substituted Pyrrolyl Alanine Derivatives. Angewandte Chemie (International Ed. in English) |
| Pomplun S, Sippel C, Hähle A, et al. (2018) Chemogenomic profiling of human and microbial FK506-binding proteins. Journal of Medicinal Chemistry |