☰

Lisa M. Ryno, Ph.D.

Affiliations: 
Chemistry Oberlin College, Oberlin, OH, United States 
Area:
chemical Biology
Website:
https://www.oberlin.edu/lisa-ryno
Google:
"Lisa M. Ryno"
Bio:

https://www.scripps.edu/newsandviews/e_20130520/graduates.html

Mean distance: 8.73
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Parents

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Jeffery W. Kelly grad student 2012 Scripps Institute
 (Adapting proteostasis through stress-responsive signaling)

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Publications

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Genereux JC, Qu S, Zhou M, et al. (2015) Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. The Embo Journal. 34: 4-19
Cooley CB, Ryno LM, Plate L, et al. (2014) Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain. Proceedings of the National Academy of Sciences of the United States of America. 111: 13046-51
Wang X, Cattaneo F, Ryno L, et al. (2014) The systemic amyloid precursor transthyretin (TTR)behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice Journal of Neuroscience. 34: 7253-7265
Ryno LM, Genereux JC, Naito T, et al. (2014) Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1. Acs Chemical Biology. 9: 1273-83
Shoulders MD, Ryno LM, Cooley CB, et al. (2013) Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells. Journal of the American Chemical Society. 135: 8129-32
Ryno LM, Wiseman RL, Kelly JW. (2013) Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases. Current Opinion in Chemical Biology. 17: 346-52
Shoulders MD, Ryno LM, Genereux JC, et al. (2013) Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments. Cell Reports. 3: 1279-92
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