Xiaochun Li
Affiliations: | 2017- | Molecular Genetics | University of Texas Southwestern Medical Center, Dallas, TX, United States |
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Structural BiologyGoogle:
"Xiaochun Li"Mean distance: (not calculated yet)
Parents
Sign in to add mentorYigong Shi | grad student | 2008-2012 | Tsinghua University |
Günter Blobel | post-doc | 2012-2017 | Rockefeller |
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Publications
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Chen H, Qi X, Faulkner RA, et al. (2022) Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nature Communications. 13: 4273 |
Long T, Debler EW, Li X. (2022) Structural enzymology of cholesterol biosynthesis and storage. Current Opinion in Structural Biology. 74: 102369 |
Qi X, Friedberg L, De Bose-Boyd R, et al. (2020) Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling. Nature Chemical Biology |
Wang R, Long T, Hassan A, et al. (2020) Cryo-EM structures of intact V-ATPase from bovine brain. Nature Communications. 11: 3921 |
Long T, Sun Y, Hassan A, et al. (2020) Structure of nevanimibe-bound tetrameric human ACAT1. Nature. 581: 339-343 |
Long T, Qi X, Hassan A, et al. (2020) Structural basis for itraconazole-mediated NPC1 inhibition. Nature Communications. 11: 152 |
Long T, Hassan A, Thompson BM, et al. (2019) Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition. Nature Communications. 10: 2452 |
Fine M, Schmiege P, Li X. (2018) Structural basis for PtdInsP-mediated human TRPML1 regulation. Nature Communications. 9: 4192 |
Qi X, Schmiege P, Coutavas E, et al. (2018) Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex. Science (New York, N.Y.) |
Qi X, Schmiege P, Coutavas E, et al. (2018) Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature |