Harry V. Gelboin

Affiliations: 
Molecular Carcinogenesis National Cancer Institute, Rockville, MD, United States 
Area:
cytochrome P450 metabolism of carcinogens and drugs
Website:
http://dx.doi.org/10.1093/carcin/bgq093
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"Harry V. Gelboin"
Bio:

(1929 - 2010)
http://home.ccr.cancer.gov/metabolism/hvgccr.htm
http://www3.cancer.gov/intra/lmc/hvg.htm
http://carcin.oxfordjournals.org/content/31/7/1308.full.pdf

Mean distance: 9.99
 
SNBCP

Parents

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James A. Miller grad student 1958 UW Madison
 (In vivo and in vitro studies on the formation of protein-bound derivatives of aminoazo dyes by rat liver)
Elizabeth Cavert Miller grad student 1958 UW Madison
Giulio L. Cantoni post-doc 1958-1961 NIH
Louis Sokoloff post-doc 1958-1961 NIMH

Children

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Lawrence A. Loeb research assistant 1962-1964 National Cancer Institute
James P. Whitlock, Jr. grad student 1975 NIH (Neurotree)
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Publications

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Chou YC, Chung YT, Liu TY, et al. (2010) The oxidative metabolism of dimemorfan by human cytochrome p450 enzymes Journal of Pharmaceutical Sciences. 99: 1063-1077
Letchoumy PV, Mohan KVPC, Stegeman JJ, et al. (2008) In vitro antioxidative potential of lactoferrin and black tea polyphenols and protective effects in vivo on carcinogen activation, DNA damage, proliferation, invasion, and angiogenesis during experimental oral carcinogenesis Oncology Research. 17: 193-203
Vidjaya Letchoumy P, Chandra Mohan KVP, Stegeman JJ, et al. (2008) Pretreatment with black tea polyphenols modulates xenobiotic-metabolizing enzymes in an experimental oral carcinogenesis model Oncology Research. 17: 75-85
Elovaara E, Stockmann-Juvala H, Mikkola J, et al. (2007) Interactive effects of methyl tertiary-butyl ether (MTBE) and tertiary-amyl methyl ether (TAME), ethanol and some drugs: Triglyceridemia, liver toxicity and induction of CYP (2E1, 2B1) and phase II enzymes in female Wistar rats Environmental Toxicology and Pharmacology. 23: 64-72
Gelboin HV, Krausz K. (2006) Monoclonal antibodies and multifunctional cytochrome P450: Drug metabolism as paradigm Journal of Clinical Pharmacology. 46: 353-372
Xiao YF, Ke Q, Seubert JM, et al. (2004) Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. Molecular Pharmacology. 66: 1607-16
Ufer M, Svensson JO, Krausz KW, et al. (2004) Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro European Journal of Clinical Pharmacology. 60: 173-182
Hu Y, Krausz K, Gelboin HV, et al. (2004) CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: Use of inhibitory monoclonal antibodies in P450 identification Xenobiotica. 34: 117-132
Soars MG, Gelboin HV, Krausz KW, et al. (2003) A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology British Journal of Clinical Pharmacology. 55: 175-181
Kutlu T, Gelboin HV, Gozukara EM. (2002) Cigarette smoking and secondary smoke in Turkey: Effect on placental aryl hydrocarbon hydroxylase (AHH), infant birth weight, and size Bulletin of Environmental Contamination and Toxicology. 69: 855-862
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