Greg Thurber

2008 Chemical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
"Greg Thurber"
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Menezes B, Khera E, Calopiz M, et al. (2022) Pharmacokinetics and Pharmacodynamics of TAK-164 Antibody Drug Conjugate Coadministered with Unconjugated Antibody. The Aaps Journal. 24: 107
Evans R, Thurber GM. (2022) Design of high avidity and low affinity antibodies for in situ control of antibody drug conjugate targeting. Scientific Reports. 12: 7677
Menezes B, Linderman JJ, Thurber GM. (2022) Simulating the Selection of Resistant Cells with Bystander Killing and Antibody Coadministration in Heterogeneous Human Epidermal Growth Factor Receptor 2-Positive Tumors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 50: 8-16
Khera E, Dong S, Huang H, et al. (2021) Cellular-Resolution Imaging of Bystander Payload Tissue Penetration from Antibody-Drug Conjugates. Molecular Cancer Therapeutics
Nessler I, Menezes B, Thurber GM. (2021) Key metrics to expanding the pipeline of successful antibody-drug conjugates. Trends in Pharmacological Sciences. 42: 803-812
Khera E, Cilliers C, Smith MD, et al. (2020) Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping. Neoplasia (New York, N.Y.). 23: 210-221
Ponte JF, Lanieri L, Khera E, et al. (2020) Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy. Molecular Cancer Therapeutics
Lu G, Nishio N, van den Berg NS, et al. (2020) Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates. Nature Communications. 11: 5667
Nessler I, Cilliers C, Thurber GM. (2020) Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging. Pharmaceutics. 12
Menezes B, Cilliers C, Wessler T, et al. (2020) An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens. The Aaps Journal. 22: 29
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