Greg Thurber
Affiliations: | 2008 | Chemical Engineering | Massachusetts Institute of Technology, Cambridge, MA, United States |
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| Menezes B, Khera E, Calopiz M, et al. (2022) Pharmacokinetics and Pharmacodynamics of TAK-164 Antibody Drug Conjugate Coadministered with Unconjugated Antibody. The Aaps Journal. 24: 107 |
| Evans R, Thurber GM. (2022) Design of high avidity and low affinity antibodies for in situ control of antibody drug conjugate targeting. Scientific Reports. 12: 7677 |
| Menezes B, Linderman JJ, Thurber GM. (2022) Simulating the Selection of Resistant Cells with Bystander Killing and Antibody Coadministration in Heterogeneous Human Epidermal Growth Factor Receptor 2-Positive Tumors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 50: 8-16 |
| Khera E, Dong S, Huang H, et al. (2021) Cellular-Resolution Imaging of Bystander Payload Tissue Penetration from Antibody-Drug Conjugates. Molecular Cancer Therapeutics |
| Nessler I, Menezes B, Thurber GM. (2021) Key metrics to expanding the pipeline of successful antibody-drug conjugates. Trends in Pharmacological Sciences. 42: 803-812 |
| Khera E, Cilliers C, Smith MD, et al. (2020) Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping. Neoplasia (New York, N.Y.). 23: 210-221 |
| Ponte JF, Lanieri L, Khera E, et al. (2020) Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy. Molecular Cancer Therapeutics |
| Lu G, Nishio N, van den Berg NS, et al. (2020) Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates. Nature Communications. 11: 5667 |
| Nessler I, Cilliers C, Thurber GM. (2020) Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging. Pharmaceutics. 12 |
| Menezes B, Cilliers C, Wessler T, et al. (2020) An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens. The Aaps Journal. 22: 29 |