Jimin Hwang
Affiliations: | Max Planck Institute for Molecular Physiology |
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| Hommen P, Hwang J, Huang F, et al. (2023) Chromenopyrazole-peptide conjugates as small-molecule based inhibitors disrupting the protein-RNA interaction of LIN28-let-7. Chembiochem : a European Journal of Chemical Biology. e202300376 |
| Hwang J, Haacke N, Borgelt L, et al. (2023) Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry. 256: 115439 |
| Borgelt L, Haacke N, Lampe P, et al. (2022) Small-molecule screening of ribonuclease L binders for RNA degradation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 154: 113589 |
| Hwang J, Qiu X, Borgelt L, et al. (2022) Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents. Bioorganic & Medicinal Chemistry. 58: 116653 |
| Hwang J, Strange N, Mazraani R, et al. (2021) Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia. European Journal of Medicinal Chemistry. 230: 114064 |
| Hwang J, Strange N, Phillips MJA, et al. (2021) Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues. European Journal of Medicinal Chemistry. 224: 113692 |
| Borgelt L, Li F, Hommen P, et al. (2021) Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and . Acs Medicinal Chemistry Letters. 12: 893-898 |
| Hwang J, Borgelt L, Wu P. (2020) Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines. Acs Combinatorial Science |
| Agbowuro AA, Hwang J, Peel E, et al. (2019) Structure-activity analysis of peptidic Chlamydia HtrA inhibitors. Bioorganic & Medicinal Chemistry |