Sebastian Fica
Affiliations: | University of Chicago, Chicago, IL |
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| Parker MT, Fica SM, Simpson GG. (2025) RNA splicing: a split consensus reveals two major 5' splice site classes. Open Biology. 15: 240293 |
| Aupič J, Borišek J, Fica SM, et al. (2023) Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome. Nature Communications. 14: 8482 |
| Parker MT, Fica SM, Barton GJ, et al. (2023) Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K. Elife. 12 |
| Parker MT, Soanes BK, Kusakina J, et al. (2022) mA modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site. Elife. 11 |
| Strittmatter LM, Capitanchik C, Newman AJ, et al. (2021) psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nature Communications. 12: 1488 |
| Fica SM. (2020) Cryo-EM snapshots of the human spliceosome reveal structural adaptions for splicing regulation. Current Opinion in Structural Biology. 65: 139-148 |
| Fica SM, Oubridge C, Wilkinson ME, et al. (2019) A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science (New York, N.Y.) |
| Wilkinson ME, Fica SM, Galej WP, et al. (2017) Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science (New York, N.Y.) |
| Fica SM, Nagai K. (2017) Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine. Nature Structural & Molecular Biology. 24: 791-799 |
| Fica SM, Oubridge C, Galej WP, et al. (2017) Structure of a spliceosome remodelled for exon ligation. Nature |