Manfred Jung

Affiliations: 
Albert-Ludwigs-University Freiburg, Freiburg im Breisgau, Baden-Württemberg, Germany 
Area:
Medicinal Chemistry, Chemical Epigenetics
Website:
http://www.pharmazie.uni-freiburg.de/chemie/german/professoren/akjunghp/
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"Manfred Jung"
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Publications

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Campiani G, Cavella C, Osko JD, et al. (2021) Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors. Journal of Medicinal Chemistry
Luise C, Robaa D, Regenass P, et al. (2021) Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors. International Journal of Molecular Sciences. 22
Fuhrmann L, Lindner S, Hauser AT, et al. (2021) Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development. International Journal of Molecular Sciences. 22
Vaca HR, Celentano AM, Toscanini MA, et al. (2021) The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs. Plos Neglected Tropical Diseases. 15: e0009226
Saraswati AP, Relitti N, Brindisi M, et al. (2020) Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation. Acs Medicinal Chemistry Letters. 11: 2268-2276
Relitti N, Saraswati AP, Chemi G, et al. (2020) Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation. European Journal of Medicinal Chemistry. 112998
Glas C, Dietschreit JCB, Wössner N, et al. (2020) Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations. European Journal of Medicinal Chemistry. 206: 112676
Reiner D, Seifert L, Deck C, et al. (2020) Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H receptor for Prader-Willi Syndrome. Scientific Reports. 10: 13558
Breit B, Lutterbeck M, Liebich A, et al. (2020) Syntheses of Thailandepsin B Pseudo-Natural Products: Access to new highly potent HDAC Inhibitors via Late Stage Modification. Chemistry (Weinheim An Der Bergstrasse, Germany)
Schiedel M, Lehotzky A, Szunyogh S, et al. (2020) HaloTag-targeted Sirtuin rearranging ligand (SirReal) for the development of proteolysis targeting chimeras (PROTACs) against the lysine deacetylase Sirtuin 2 (Sirt2). Chembiochem : a European Journal of Chemical Biology
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