Matthias Schiedel, PhD
Affiliations: | Pharmacy | University of Erlangen, Erlangen, Bayern, Germany |
Area:
Medicinal ChemistryWebsite:
https://www.chemie.nat.fau.de/person/matthias-schiedel/Google:
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Publications
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| Laurin CMC, Bluck JP, Chan AKN, et al. (2020) Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of . Acs Infectious Diseases |
| Schiedel M, Lehotzky A, Szunyogh S, et al. (2020) HaloTag-targeted Sirtuin rearranging ligand (SirReal) for the development of proteolysis targeting chimeras (PROTACs) against the lysine deacetylase Sirtuin 2 (Sirt2). Chembiochem : a European Journal of Chemical Biology |
| Schiedel M, Daub H, Itzen A, et al. (2020) Front Cover: Validation of the Slow Off‐Kinetics of Sirtuin‐Rearranging Ligands (SirReals) by Means of Label‐Free Electrically Switchable Nanolever Technology (ChemBioChem 8/2020) Chembiochem. 21: 1050-1050 |
| Schiedel M, Daub H, Itzen A, et al. (2019) Validation of slow off-kinetics of Sirtuin Rearranging Ligands (SirReals) by means of the label-free electrically switchable nanolever technology. Chembiochem : a European Journal of Chemical Biology |
| Schiedel M, Moroglu M, Ascough DMH, et al. (2019) Chemical epigenetics: the impact of chemical- and chemical biology techniques on bromodomain target validation. Angewandte Chemie (International Ed. in English) |
| Schiedel M, Conway SJ. (2018) Small molecules as tools to study the chemical epigenetics of lysine acetylation. Current Opinion in Chemical Biology. 45: 166-178 |
| Robaa D, Monaldi D, Wössner N, et al. (2018) Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 - New Opportunities, New Questions. Chemical Record (New York, N.Y.) |
| Jennings LE, Schiedel M, Hewings DS, et al. (2018) BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. Bioorganic & Medicinal Chemistry |
| Swyter S, Schiedel M, Monaldi D, et al. (2018) New chemical tools for probing activity and inhibition of the NAD-dependent lysine deacylase sirtuin 2. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373 |
| Schiedel M, Fallarero A, Luise C, et al. (2017) Synthesis and biological evaluation of 8-hydroxy-2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Medchemcomm. 8: 465-470 |