Matthias Schiedel, PhD
Affiliations: | Pharmacy | University of Erlangen, Erlangen, Bayern, Germany |
Area:
Medicinal ChemistryWebsite:
https://www.chemie.nat.fau.de/person/matthias-schiedel/Google:
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Publications
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| Schiedel M, McArdle DJB, Padalino G, et al. (2023) Small Molecule Ligands of the BET-like Bromodomain, BRD3, Affect Survival, Oviposition, and Development. Journal of Medicinal Chemistry |
| Sinatra L, Vogelmann A, Friedrich F, et al. (2023) Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. Journal of Medicinal Chemistry. 66: 14787-14814 |
| Thomas AM, Serafini M, Grant EK, et al. (2023) Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation. Acs Chemical Biology |
| Huber ME, Toy L, Schmidt MF, et al. (2022) Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs. Chemistry (Weinheim An Der Bergstrasse, Germany). e202202565 |
| Vogelmann A, Jung M, Hansen FK, et al. (2022) Comparison of Cellular Target Engagement Methods for the Tubulin Deacetylases Sirt2 and HDAC6: NanoBRET, CETSA, Tubulin Acetylation, and PROTACs. Acs Pharmacology & Translational Science. 5: 138-140 |
| Brand M, Clayton J, Moroglu M, et al. (2021) Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of Medicinal Chemistry |
| Laurin CMC, Bluck JP, Chan AKN, et al. (2020) Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of . Acs Infectious Diseases |
| Schiedel M, Lehotzky A, Szunyogh S, et al. (2020) HaloTag-targeted Sirtuin rearranging ligand (SirReal) for the development of proteolysis targeting chimeras (PROTACs) against the lysine deacetylase Sirtuin 2 (Sirt2). Chembiochem : a European Journal of Chemical Biology |
| Schiedel M, Daub H, Itzen A, et al. (2020) Front Cover: Validation of the Slow Off‐Kinetics of Sirtuin‐Rearranging Ligands (SirReals) by Means of Label‐Free Electrically Switchable Nanolever Technology (ChemBioChem 8/2020) Chembiochem. 21: 1050-1050 |
| Schiedel M, Daub H, Itzen A, et al. (2019) Validation of slow off-kinetics of Sirtuin Rearranging Ligands (SirReals) by means of the label-free electrically switchable nanolever technology. Chembiochem : a European Journal of Chemical Biology |