Brian A. Joughin

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
computational biology, cancer biology, systems biology
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"Brian Joughin"
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Parents

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Bruce Tidor grad student 2001-2006 MIT
Michael B. Yaffe grad student 2001-2006 MIT
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Publications

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Yaron-Barir TM, Joughin BA, Huntsman EM, et al. (2024) The intrinsic substrate specificity of the human tyrosine kinome. Nature
van de Kooij B, van der Wal FJ, Rother MB, et al. (2023) The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks. Biorxiv : the Preprint Server For Biology
Green BL, Gamble LA, Diggs LP, et al. (2023) Early immune changes support signet ring cell dormancy in CDH1-driven hereditary diffuse gastric carcinogenesis. Molecular Cancer Research : McR
Netterfield TS, Ostheimer GJ, Tentner AR, et al. (2023) Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition. Cell Systems. 14: 582-604.e10
Goretti Riça I, Joughin BA, Teke ME, et al. (2022) Neutrophil heterogeneity and emergence of a distinct population of CD11b/CD18-activated low-density neutrophils after trauma. The Journal of Trauma and Acute Care Surgery. 94: 187-196
Moore HB, Neal MD, Bertolet M, et al. (2022) Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion. Annals of Surgery Open : Perspectives of Surgical History, Education, and Clinical Approaches. 3
Sriram G, Milling LE, Chen JK, et al. (2021) The injury response to DNA damage in live tumor cells promotes antitumor immunity. Science Signaling. 14: eabc4764
Cahill LA, Joughin BA, Kwon WY, et al. (2020) Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper. Annals of Surgery. 272: 604-610
Krismer K, Bird MA, Varmeh S, et al. (2020) Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression. Cell Reports. 32: 108064
Stopfer LE, Mesfin JM, Joughin BA, et al. (2020) Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition. Nature Communications. 11: 2760
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