William A. Frazier, Ph.D.
Affiliations: | 1976- | Biochemistry and Molecular Biophysics | Washington University, Saint Louis, St. Louis, MO |
Area:
NO signalingWebsite:
http://biochem.wustl.edu/faculty/faculty/william-frazierGoogle:
"William Frazier"Mean distance: 9.38 | S | N | B | C | P |
Parents
Sign in to add mentor| Ralph A. Bradshaw | grad student | 1973 | Washington University | |
| (Nerve growth factor: studies on the structure, function and mechanism) | ||||
| Samuel H. Barondes | post-doc | 1974-1976 | UCSD | |
Children
Sign in to add trainee| Allyson L. Anding | research assistant | ||
| Vishva M. Dixit | post-doc | 1986 | Washington University |
BETA: Related publications
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Publications
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| Puro RJ, Bouchlaka MN, Hiebsch RR, et al. (2019) Development of AO-176, a Next Generation Humanized Anti-CD47 Antibody With Novel Anti-Cancer Properties and Negligible Red Blood Cell Binding. Molecular Cancer Therapeutics |
| Liu X, Pu Y, Cron K, et al. (2015) CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Nature Medicine |
| Frazier W, Liu K, Dimitry J, et al. (2015) Abstract 2: Phosphorylation of BNIP3 is a switch between life and death in cancer cells Cancer Research. 75: 2-2 |
| Manning PT, Capoccia BJ, Rettig MP, et al. (2014) Dual-Function Anti-CD47mAbs Induce Tumor Cell Death and Promote Phagocytosis Resulting in Enhanced in Vivo Efficacy Blood. 124: 991-991 |
| Azcutia V, Routledge M, Williams MR, et al. (2013) CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions. Molecular Biology of the Cell. 24: 3358-68 |
| Soto-Pantoja DR, Miller TW, Frazier WA, et al. (2012) Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies. Proceedings of the National Academy of Sciences of the United States of America. 109: E2842; author reply |
| Isenberg JS, Annis DS, Pendrak ML, et al. (2009) Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses. The Journal of Biological Chemistry. 284: 1116-25 |
| Isenberg JS, Frazier WA, Krishna MC, et al. (2008) Enhancing cardiovascular dynamics by inhibition of thrombospondin-1/CD47 signaling. Current Drug Targets. 9: 833-41 |
| Isenberg JS, Frazier WA, Roberts DD. (2008) Thrombospondin-1: a physiological regulator of nitric oxide signaling. Cellular and Molecular Life Sciences : Cmls. 65: 728-42 |
| Isenberg JS, Roberts DD, Frazier WA. (2008) CD47: a new target in cardiovascular therapy. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 615-21 |