Thu Thuy T Dang

Chemistry University of British Columbia, Okanagan 
biosynthesis of natural products, biological chemistry, cytochrome P450s
"Thu Thuy Dang"
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Peter J. Facchini grad student 2009-2014 University of Calgary (Cell Biology Tree)
Sarah Ellen O'Connor post-doc 2015-2018 John Innes Center
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Brose J, Lau KH, Dang TTT, et al. (2021) The Mitragyna speciosa (Kratom) Genome: A resource for data-mining potent pharmaceuticals that impact human health. G3 (Bethesda, Md.)
Nguyen TD, Dang TT. (2021) Demystifying the momilactone pathway. Nature Chemical Biology. 17: 126-128
Nguyen T, Dang TT. (2021) Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants Frontiers in Plant Science. 12
Nguyen TD, Riordan-Short S, Dang TT, et al. (2020) Quantitation of Select Terpenes/Terpenoids and Nicotine Using Gas Chromatography-Mass Spectrometry with High-Temperature Headspace Sampling. Acs Omega. 5: 5565-5573
Dang TT, Franke J, Carqueijeiro IST, et al. (2018) Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes. Nature Chemical Biology
Carqueijeiro IT, Brown S, Chung K, et al. (2018) Two tabersonine 6,7-epoxidases start synthesis of lochnericine-type alkaloids in Catharanthus roseus. Plant Physiology
Caputi L, Franke J, Farrow SC, et al. (2018) Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle. Science (New York, N.Y.)
Carqueijeiro I, Dugé de Bernonville T, Lanoue A, et al. (2018) A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids. The Plant Journal : For Cell and Molecular Biology
Stavrinides A, Tatsis E, Dang TT, et al. (2018) Discovery of a short chain dehydrogenase from Catharanthus roseus that produces a novel monoterpene indole alkaloid. Chembiochem : a European Journal of Chemical Biology
Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, et al. (2017) A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate. Nature Communications. 8: 316
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