A Ganesan

University of East Anglia, Norwich, England, United Kingdom 
Chemical biology, medicinal chemistry
"A Ganesan"
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Coutinho Carneiro V, de Abreu da Silva IC, Amaral MS, et al. (2020) Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni. Plos Neglected Tropical Diseases. 14: e0008332
Ho T, Chan A, Ganesan A. (2020) Thirty years of HDAC inhibitors: 2020 hindsight. Journal of Medicinal Chemistry
Liang L, Wang H, Du Y, et al. (2020) New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation. Bioorganic Chemistry. 99: 103808
Ferreira GM, Magalhães JG, Maltarollo VG, et al. (2019) QSAR studies on the human sirtuin 2 inhibition by non-covalent 7,5,2-anilinobenzamide derivatives. Journal of Biomolecular Structure & Dynamics. 1-10
Vaidergorn MM, Carneiro ZA, Lopes CD, et al. (2018) β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders. European Journal of Medicinal Chemistry. 157: 657-664
Regufe da Mota S, Bailey S, Strivens RA, et al. (2018) LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models. Cancer Cell International. 18: 71
Ganesan A. (2018) Epigenetic drug discovery: a success story for cofactor interference. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373
Lecointre B, Narozny R, Borrello MT, et al. (2018) Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373
Silva AC, Benelkebir H, Lopes RSC, et al. (2018) Total Synthesis of Altissimacoumarin D, a Small Molecule Sirtuin1 Activator Journal of the Brazilian Chemical Society
Conforti F, Davies ER, Calderwood CJ, et al. (2017) The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis. Oncotarget
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