A Ganesan
Affiliations: | University of East Anglia, Norwich, England, United Kingdom |
Area:
Chemical biology, medicinal chemistryGoogle:
"A Ganesan"Mean distance: 7.61 | S | N | B | C | P |
Parents
Sign in to add mentor| Clayton H. Heathcock | grad student | 1986-1992 | HHMI, University of California-Berkeley |
| Gregory L. Verdine | post-doc | 1992-1993 | Harvard |
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Publications
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| Coutinho Carneiro V, de Abreu da Silva IC, Amaral MS, et al. (2020) Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni. Plos Neglected Tropical Diseases. 14: e0008332 |
| Ho T, Chan A, Ganesan A. (2020) Thirty years of HDAC inhibitors: 2020 hindsight. Journal of Medicinal Chemistry |
| Liang L, Wang H, Du Y, et al. (2020) New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation. Bioorganic Chemistry. 99: 103808 |
| Ferreira GM, Magalhães JG, Maltarollo VG, et al. (2019) QSAR studies on the human sirtuin 2 inhibition by non-covalent 7,5,2-anilinobenzamide derivatives. Journal of Biomolecular Structure & Dynamics. 1-10 |
| Vaidergorn MM, Carneiro ZA, Lopes CD, et al. (2018) β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders. European Journal of Medicinal Chemistry. 157: 657-664 |
| Regufe da Mota S, Bailey S, Strivens RA, et al. (2018) LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models. Cancer Cell International. 18: 71 |
| Ganesan A. (2018) Epigenetic drug discovery: a success story for cofactor interference. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373 |
| Lecointre B, Narozny R, Borrello MT, et al. (2018) Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373 |
| Silva AC, Benelkebir H, Lopes RSC, et al. (2018) Total Synthesis of Altissimacoumarin D, a Small Molecule Sirtuin1 Activator Journal of the Brazilian Chemical Society |
| Conforti F, Davies ER, Calderwood CJ, et al. (2017) The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis. Oncotarget |