Elizabeth Rodkey
Affiliations: | 2007-2012 | Case Western Reserve University, Cleveland Heights, OH, United States |
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| Che T, Rodkey EA, Bethel CR, et al. (2015) Detecting a quasi-stable imine species on the reaction pathway of SHV-1 β-lactamase and 6β-(hydroxymethyl)penicillanic acid sulfone. Biochemistry. 54: 734-43 |
| Rodkey EA, Winkler ML, Bethel CR, et al. (2014) Penam sulfones and β-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition. Plos One. 9: e85892 |
| Rodkey EA, McLeod DC, Bethel CR, et al. (2013) β-Lactamase inhibition by 7-alkylidenecephalosporin sulfones: allylic transposition and formation of an unprecedented stabilized acyl-enzyme. Journal of the American Chemical Society. 135: 18358-69 |
| Winkler ML, Rodkey EA, Taracila MA, et al. (2013) Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. Journal of Medicinal Chemistry. 56: 1084-97 |
| Rodkey EA, Drawz SM, Sampson JM, et al. (2012) Crystal structure of a preacylation complex of the β-lactamase inhibitor sulbactam bound to a sulfenamide bond-containing thiol-β-lactamase. Journal of the American Chemical Society. 134: 16798-804 |
| Ke W, Rodkey EA, Sampson JM, et al. (2012) The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants. Chemmedchem. 7: 1002-8 |
| Rodkey EA, Sampson JM, Kalp M, et al. (2011) β-Lactamase Inhibition: Mechanistic Details and Novel Inhibitors Biophysical Journal. 100: 552a |