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Engin Özkan

Affiliations: 
2014- Biochemistry and Molecular Biology University of Chicago, Chicago, IL 
Area:
Structural biology, Cell surface receptors, Molecular neurobiology, Ubiquitination
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"Engin Özkan"
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Parents

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Johann Deisenhofer grad student 1999-2006 University of Texas Southwestern Medical Center at Dallas
K. Christopher Garcia post-doc 2006-2013 Stanford

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Publications

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Priest JM, Nichols EL, Smock RG, et al. (2024) Structural insights into the formation of repulsive netrin guidance complexes. Science Advances. 10: eadj8083
Li H, Watson A, Olechwier A, et al. (2017) Deconstruction of the Beaten Path-Sidestep interaction network provides insights into neuromuscular system development. Elife. 6
Li H, Watson A, Olechwier A, et al. (2017) Author response: Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development Elife
Carrillo RA, Özkan E, Menon KP, et al. (2015) Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. Cell. 163: 1770-82
Ho CC, Guo N, Sockolosky JT, et al. (2015) "Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis. The Journal of Biological Chemistry. 290: 12650-63
Birnbaum ME, Mendoza JL, Sethi DK, et al. (2014) Deconstructing the peptide-MHC specificity of T cell recognition. Cell. 157: 1073-87
Özkan E, Chia PH, Wang RR, et al. (2014) Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis. Cell. 156: 482-94
Weiskopf K, Ring AM, Ho CC, et al. (2013) Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (New York, N.Y.). 341: 88-91
Yu XM, Gutman I, Mosca TJ, et al. (2013) Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-β signaling. Neuron. 78: 456-68
Ring AM, Lin JX, Feng D, et al. (2012) Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15. Nature Immunology. 13: 1187-95
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