Jonathan M. Elkins
Affiliations: | 1998-2002 | Chemistry | University of Oxford, Oxford, United Kingdom |
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| Moustakim M, Riedel K, Schuller M, et al. (2018) Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2. Bioorganic & Medicinal Chemistry |
| Howard-Jones AR, Elkins JM, Clifton IJ, et al. (2007) Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762 |
| Elkins JM, Kershaw NJ, Schofield CJ. (2005) X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster. The Biochemical Journal. 385: 565-73 |
| Caines ME, Elkins JM, Hewitson KS, et al. (2003) Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway. The Journal of Biological Chemistry. 279: 5685-92 |
| Elkins JM, Rutledge PJ, Burzlaff NI, et al. (2003) Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60 |
| Hewitson KS, McNeill LA, Elkins JM, et al. (2003) The role of iron and 2-oxoglutarate oxygenases in signalling. Biochemical Society Transactions. 31: 510-5 |
| Elkins JM, Hewitson KS, McNeill LA, et al. (2003) Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha. The Journal of Biological Chemistry. 278: 1802-6 |
| Elkins JM, Rutledge PJ, Burzlaff NI, et al. (2003) Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460 |
| Rutledge PJ, Burzlaff NI, Elkins JM, et al. (2002) A device for the high-pressure oxygenation of protein crystals. Analytical Biochemistry. 308: 265-8 |
| Hewitson KS, McNeill LA, Riordan MV, et al. (2002) Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. The Journal of Biological Chemistry. 277: 26351-5 |