Colin R. Jefcoate, D. Phil.

Affiliations: 
Pharmacology University of Wisconsin, Madison, Madison, WI 
Area:
Cytochromes P450, xenobiotic metabolism, steroidogenesis
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"Colin Jefcoate"
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Israel Hanukoglu grad student 1977-1980 UW Madison
Young C. Cho grad student 2003 UW Madison
Paul Robert Hanlon grad student 2003 UW Madison
Noe Galvan grad student 2004 UW Madison
Melissa Antonio Cimafranca grad student 2006 UW Madison
Haichuan Duan grad student 2007 UW Madison
Justin Bushkofsky grad student 2012 UW Madison
Jinwoo Lee grad student 2012 UW Madison
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Publications

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Jefcoate CR, Lee J. (2018) Cholesterol signaling in single cells: lessons from STAR and sm-FISH. Journal of Molecular Endocrinology. 60: R213-R235
Maguire M, Larsen MC, Foong YH, et al. (2017) Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development. Molecular and Cellular Endocrinology
Maguire M, Bushkofsky JR, Larsen MC, et al. (2017) Diet-dependent retinoid effects on liver gene expression include stellate and inflammation markers and parallel effects of the nuclear repressor Shp. The Journal of Nutritional Biochemistry. 47: 63-74
Larsen MC, N'Jai AU, Alexander DL, et al. (2016) Cyp1b1-mediated suppression of lymphoid progenitors in bone marrow by polycyclic aromatic hydrocarbons coordinately impacts spleen and thymus: a selective role for the Ah Receptor. Pharmacology Research & Perspectives. 4: e00245
Rondelli CM, Larsen MC, N'jai A, et al. (2016) PAHs Target Hematopoietic Linages in Bone Marrow through Cyp1b1 Primarily in Mesenchymal Stromal Cells but Not AhR: A Reconstituted In Vitro Model. Stem Cells International. 2016: 1753491
Kim SH, Trinh AT, Larsen MC, et al. (2016) Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism. Nucleic Acids Research
Dinu D, Chu C, Veith A, et al. (2016) Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury. Biochemical and Biophysical Research Communications
Bushkofsky JR, Maguire M, Larsen MC, et al. (2016) Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα. Archives of Biochemistry and Biophysics
Larsen MC, Bushkofsky JR, Gorman T, et al. (2015) Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. Archives of Biochemistry and Biophysics. 571: 21-39
Lee J, Tong T, Takemori H, et al. (2015) Stimulation of StAR expression by cAMP is controlled by inhibition of highly inducible SIK1 via CRTC2, a co-activator of CREB. Molecular and Cellular Endocrinology. 408: 80-9
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