Kelvin K. Ogilvie, PhD
Affiliations: | 1974-1987 | Chemistry | McGill University, Montreal, QC, Canada |
Website:
http://www.science.ca/scientists/scientistprofile.php?pID=203Google:
"Kelvin K. Ogilvie"Bio:
National Institute of Dental and Craniofacial Research and McGill University
DOI: 10.1021/ja01040a042
Mean distance: 8.42 | S | N | B | C | P |
Parents
Sign in to add mentor| Robert Lewis Letsinger | grad student | 1968 | Northwestern | |
| (A triester approach to oligonucleotide synthesis) | ||||
Children
Sign in to add trainee| Masad J. Damha | grad student | 1987 | McGill |
| Youla Tsantrizos | grad student | 1987-1990 | McGill |
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Publications
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| Brodney MA, Beck EM, Butler CR, et al. (2015) Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors. Journal of Medicinal Chemistry. 58: 3223-52 |
| Butler CR, Brodney MA, Beck EM, et al. (2015) Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design. Journal of Medicinal Chemistry. 58: 2678-702 |
| Huang J, Ishino T, Chen G, et al. (2013) Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody Journal of Pharmacology and Experimental Therapeutics. 346: 270-280 |
| Lee CW, Lira R, Dutra J, et al. (2013) Stereoselective synthesis of spiropiperidines as BACE-1 aspartyl protease inhibitors via late stage N-arylation of a 1,8-diazaspiro[4.5]dec-3-en-2-one pharmacophore. The Journal of Organic Chemistry. 78: 2661-9 |
| Ogilvie K, Jelavic M. (2013) Grade inflation in the US higher educational environment: A faculty perception study International Journal of Management in Education. 7: 406-416 |
| Brodney MA, Barreiro G, Ogilvie K, et al. (2012) Spirocyclic sulfamides as β-secretase 1 (BACE-1) inhibitors for the treatment of Alzheimer's disease: utilization of structure based drug design, WaterMap, and CNS penetration studies to identify centrally efficacious inhibitors. Journal of Medicinal Chemistry. 55: 9224-39 |
| Driscoll DL, Dotterrer B, Collins D, et al. (2012) Demographic and contextual factors associated with inhalant use among youth in rural Alaska. International Journal of Circumpolar Health. 71: 1-4 |
| Richards S, Larson CJ, Koltun ES, et al. (2012) Discovery and characterization of an inhibitor of glucosylceramide synthase. Journal of Medicinal Chemistry. 55: 4322-35 |
| Khanin D, Ogilvie K, Leibsohn D. (2012) International entrepreneurship, venture capital networks, and reinvestment decisions Journal of International Entrepreneurship. 10: 1-24 |
| Koltun E, Richards S, Chan V, et al. (2011) Discovery of a new class of glucosylceramide synthase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 6773-7 |