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Jack Taunton

Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
signaling proteins
"Jack Taunton"

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Stuart L. Schreiber grad student 1996 Harvard
 (Natural Born Epoxides: Synthetic and Biological Studies of Dynemicin A and Trapoxin B)
Timothy J. Mitchison post-doc Harvard Medical School


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Geoffrey Alexander Smith grad student 2011- UCSF
Carl Co grad student 2007 UCSF
Jennifer L. Garrison grad student 2001-2007 UCSF (Neurotree)
Nathan N. Gushwa grad student 2009 UCSF
Jeffrey C. Henise grad student 2011 UCSF
Andrew L. MacKinnon grad student 2011 UCSF
Jonathan W. Choy grad student 2013 UCSF
Iana M. Serafimova grad student 2013 UCSF
Rebecca L. Maglathlin grad student 2014 UCSF
Rand M. Miller grad student 2014 UCSF
Shawn Xiaohu Ouyang post-doc
Haoyuan Wang post-doc 2017- UCSF
Sumit Prakash post-doc 2016 (Neurotree)
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Fink EA, Bardine C, Gahbauer S, et al. (2023) Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors. Protein Science : a Publication of the Protein Society. e4712
Holm M, Natchiar SK, Rundlet EJ, et al. (2023) mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature
Oltion K, Carelli JD, Yang T, et al. (2023) An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes. Cell. 186: 346-362.e17
Wang HY, Yang H, Holm M, et al. (2022) Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3. Nature Chemistry
Yang T, Cuesta A, Wan X, et al. (2022) Reversible lysine-targeted probes reveal residence time-based kinase selectivity. Nature Chemical Biology
Klein VG, Bray WM, Wang HY, et al. (2021) Identifying the Cellular Target of Cordyheptapeptide A and Synthetic Derivatives. Acs Chemical Biology
Ramkumar P, Abarientos AB, Tian R, et al. (2020) CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma. Blood Advances. 4: 2899-2911
Gordon DE, Jang GM, Bouhaddou M, et al. (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature
Wan X, Yang T, Cuesta A, et al. (2020) Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking. Journal of the American Chemical Society
Cuesta A, Wan X, Burlingame AL, et al. (2020) Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90. Journal of the American Chemical Society
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