Parents

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Frank W. Fitch grad student 1978 Chicago
 (Regulation of cytolytic t lymphocyte generation in rat transplantation immunity)

Children

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Geoffrey Alexander Smith grad student 2011- UCSF
Ravindra Majeti grad student 2000 UCSF
Jen Liou grad student 2001 UCSF
Tomasz Sosinowski grad student 2001 UCSF
Gregory M. Ku grad student 2002 UCSF
Zheng Xu grad student 2002 UCSF
Joseph Lin grad student 2003 UCSF
Margaret D. Myers grad student 2005 UCSF
Vikas Gupta grad student 2007 UCSF
Susan E. Levin grad student 2007 UCSF
Emil H. Palacios grad student 2007 UCSF
Marcus A. Zachariah grad student 2010 UCSF
Ying Xim Tan grad student 2013 UCSF
Tanya S. Freedman post-doc
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Publications

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Eggert J, Zinzow-Kramer WM, Hu Y, et al. (2024) Cbl-b mitigates the responsiveness of naive CD8 T cells that experience extensive tonic T cell receptor signaling. Science Signaling. 17: eadh0439
Tsai YL, Arias-Badia M, Kadlecek TA, et al. (2023) TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments. Immunity. 56: 2682-2698.e9
Weiss A. (2023) Peeking Into the Black Box of T Cell Receptor Signaling. Annual Review of Immunology
Nguyen TTT, Lu W, Zhu WS, et al. (2023) Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300987120
Lo WL, Kuhlmann M, Rizzuto G, et al. (2023) A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature Immunology
Eggert J, Zinzow-Kramer WM, Hu Y, et al. (2023) Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness. Biorxiv : the Preprint Server For Biology
Lu W, Helou YA, Shrinivas K, et al. (2022) The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P replenishment in response to TCR signaling during T cell development and survival. Nature Immunology. 24: 136-147
Horkova V, Drobek A, Paprckova D, et al. (2022) Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature Immunology. 24: 174-185
Ashouri JF, Lo WL, Nguyen TTT, et al. (2021) ZAP70, too little, too much can lead to autoimmunity. Immunological Reviews
Huang F, Nguyen TT, Echeverria I, et al. (2021) Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. Elife. 10
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