Tim Clausen
Affiliations: | 2002- | IMP Vienna |
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Sign in to add mentorRobert Huber | grad student | 1997 | Max Planck Institute of Biochemistry, Martinsried |
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Publications
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Morreale FE, Kleine S, Leodolter J, et al. (2022) BacPROTACs mediate targeted protein degradation in bacteria. Cell |
Rey J, Breiden M, Lux V, et al. (2022) An allosteric HTRA1-calpain 2 complex with restricted activation profile. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113520119 |
Hawkins PME, Hoi DM, Cheung CY, et al. (2022) Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A. Journal of Medicinal Chemistry |
Cable J, Weber-Ban E, Clausen T, et al. (2022) Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report. Annals of the New York Academy of Sciences |
Hajdusits B, Suskiewicz MJ, Hundt N, et al. (2021) McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. Elife. 10 |
Grabarczyk DB, Petrova OA, Deszcz L, et al. (2021) HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nature Chemical Biology |
Rodriguez Carvajal A, Grishkovskaya I, Gomez Diaz C, et al. (2021) The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains. Elife. 10 |
Asanović I, Strandback E, Kroupova A, et al. (2021) The oxidoreductase PYROXD1 uses NAD(P) as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Molecular Cell |
Stephani M, Picchianti L, Gajic A, et al. (2020) A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress. Elife. 9 |
Beveridge R, Kessler D, Rumpel K, et al. (2020) Native Mass Spectrometry Can Effectively Predict PROTAC Efficacy. Acs Central Science. 6: 1223-1230 |