Simon J. Boulton
Affiliations: | Cancer Research UK - London Research Institute |
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Parents
Sign in to add mentor| Stephen P. Jackson | grad student | 1994-1998 | (Neurotree) |
| Marc Vidal | post-doc | 1998-2002 | Harvard Medical School (Neurotree) |
Children
Sign in to add trainee| Dragana Ahel | post-doc | 2004-2009 | Cancer Research UK - London Research Institute |
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Publications
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| Borel V, Boeing S, Van Wietmarschen N, et al. (2022) Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis. Cell Reports. 39: 110871 |
| Bayley R, Borel V, Moss RJ, et al. (2022) H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ. Molecular Cell |
| Silva N, Castellano-Pozo M, Matsuzaki K, et al. (2022) Proline-specific aminopeptidase P prevents replication-associated genome instability. Plos Genetics. 18: e1010025 |
| Anand R, Buechelmaier E, Belan O, et al. (2021) HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51. Nature |
| Špírek M, Taylor MRG, Belan O, et al. (2021) Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function. Nature Communications. 12: 5545 |
| Bacic L, Gaullier G, Sabantsev A, et al. (2021) Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 10 |
| Chapman JR, Barral P, Vannier JB, et al. (2021) RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection. Molecular Cell. 81: 2868 |
| Belan O, Anand R, Boulton SJ. (2021) Mechanism of mitotic recombination: insights from C. elegans. Current Opinion in Genetics & Development. 71: 10-18 |
| Zatreanu D, Robinson HMR, Alkhatib O, et al. (2021) Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nature Communications. 12: 3636 |
| Meier B, Volkova NV, Hong Y, et al. (2021) Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation. Plos One. 16: e0250291 |