Simon J. Boulton

Cancer Research UK - London Research Institute 
"Simon Boulton"
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Stephen P. Jackson grad student 1994-1998 (Neurotree)
Marc Vidal post-doc 1998-2002 Harvard Medical School (Neurotree)
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Borel V, Boeing S, Van Wietmarschen N, et al. (2022) Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis. Cell Reports. 39: 110871
Bayley R, Borel V, Moss RJ, et al. (2022) H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ. Molecular Cell
Silva N, Castellano-Pozo M, Matsuzaki K, et al. (2022) Proline-specific aminopeptidase P prevents replication-associated genome instability. Plos Genetics. 18: e1010025
Anand R, Buechelmaier E, Belan O, et al. (2021) HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51. Nature
Špírek M, Taylor MRG, Belan O, et al. (2021) Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function. Nature Communications. 12: 5545
Bacic L, Gaullier G, Sabantsev A, et al. (2021) Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 10
Chapman JR, Barral P, Vannier JB, et al. (2021) RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection. Molecular Cell. 81: 2868
Belan O, Anand R, Boulton SJ. (2021) Mechanism of mitotic recombination: insights from C. elegans. Current Opinion in Genetics & Development. 71: 10-18
Zatreanu D, Robinson HMR, Alkhatib O, et al. (2021) Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nature Communications. 12: 3636
Meier B, Volkova NV, Hong Y, et al. (2021) Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation. Plos One. 16: e0250291
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