Simon J. Boulton

Cancer Research UK - London Research Institute 
"Simon Boulton"
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Stephen P. Jackson grad student 1994-1998 (Neurotree)
Marc Vidal post-doc 1998-2002 Harvard Medical School (Neurotree)
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Chapman JR, Barral P, Vannier JB, et al. (2021) RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection. Molecular Cell. 81: 2868
Hewitt G, Borel V, Segura-Bayona S, et al. (2020) Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Molecular Cell
Panier S, Maric M, Hewitt G, et al. (2019) SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Molecular Cell
León-Ortiz AM, Panier S, Sarek G, et al. (2018) A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination. Molecular Cell. 69: 292-305.e6
Margalef P, Kotsantis P, Borel V, et al. (2017) Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell
Sarek G, Vannier JB, Panier S, et al. (2016) TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding. Molecular Cell. 61: 788-789
Matsuzaki K, Borel V, Adelman CA, et al. (2015) FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway. Genes & Development
Chung G, Rose AM, Petalcorin MI, et al. (2015) REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans. Genes & Development. 29: 1969-79
Taylor MR, Špírek M, Chaurasiya KR, et al. (2015) Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Cell. 162: 271-86
Xu G, Chapman JR, Brandsma I, et al. (2015) REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 521: 541-4
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