Tobias Krojer

2005-2009 IMP Vienna 
 2009-2020 Centre for Medicines Discovery University of Oxford, Oxford, United Kingdom 
"Tobias Krojer"
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Ferreira IM, Edwin N Quesñay J, Bastos AC, et al. (2021) Structure and activation mechanism of the human liver-type glutaminase GLS2. Biochimie
Pfeffer I, Brewitz L, Krojer T, et al. (2019) Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nature Communications. 10: 4910
Chowdhury R, Sekirnik R, Brissett NC, et al. (2014) Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature. 510: 422-6
Horita S, Scotti J, McDonough M, et al. (2014) Crystal structures of 2OG oxygenases involved in ribosomal protein hydroxylation Acta Crystallographica Section a Foundations and Advances. 70: C304-C304
Froese DS, Forouhar F, Tran TH, et al. (2013) Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure (London, England : 1993). 21: 1182-92
Canning P, Cooper CD, Krojer T, et al. (2013) Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. The Journal of Biological Chemistry. 288: 7803-14
Froese DS, Krojer T, Wu X, et al. (2012) Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function. Biochemistry. 51: 5083-90
Sawa J, Malet H, Krojer T, et al. (2011) Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. The Journal of Biological Chemistry. 286: 30680-30690
Kochan G, Krojer T, Harvey D, et al. (2011) Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proceedings of the National Academy of Sciences of the United States of America. 108: 7745-50
Truebestein L, Tennstaedt A, Mönig T, et al. (2011) Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nature Structural & Molecular Biology. 18: 386-8
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