Stefan Knapp
Affiliations: | Oxford University UK |
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| Dötsch L, Davies C, Hennes E, et al. (2024) Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of Medicinal Chemistry. 67: 4691-4706 |
| Schweipert M, Nehls T, Frühauf A, et al. (2024) The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation. Protein Science : a Publication of the Protein Society. 33: e4917 |
| Bauer N, Balourdas DI, Schneider JR, et al. (2024) Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. Acs Chemical Biology |
| Amrhein JA, Berger LM, Balourdas DI, et al. (2023) Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of Medicinal Chemistry |
| Outhwaite IR, Singh S, Berger BT, et al. (2023) Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting. Elife. 12 |
| Sanz Murillo M, Villagran Suarez A, Dederer V, et al. (2023) Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Science Advances. 9: eadk6191 |
| Tiek D, Wells CI, Schröder M, et al. (2023) SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Current Research in Chemical Biology. 3 |
| Chauhan C, Kraemer A, Knapp S, et al. (2023) 5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling. Cell Death Discovery. 9: 262 |
| Deau E, Lindberg MF, Miege F, et al. (2023) Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B. Journal of Medicinal Chemistry |
| Amrhein JA, Wang G, Berger BT, et al. (2023) Design and Synthesis of Pyrazole-Based Macrocyclic Kinase Inhibitors Targeting BMPR2. Acs Medicinal Chemistry Letters. 14: 833-840 |