Elsje Gisela Otten

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2017- MRC LMB 
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"Elsje Gisela Otten"
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Otten EG, Werner E, Crespillo-Casado A, et al. (2021) Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection. Nature. 594: 111-116
Ravenhill BJ, Boyle KB, von Muhlinen N, et al. (2019) The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria. Molecular Cell
Otten EG, Stefanatos R, Carroll B, et al. (2018) Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions. Cell Stress. 2: 91-93
Carroll B, Otten EG, Manni D, et al. (2018) Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nature Communications. 9: 256
Rabanal-Ruiz Y, Otten EG, Korolchuk VI. (2017) mTORC1 as the main gateway to autophagy. Essays in Biochemistry. 61: 565-584
Hallam D, Collin J, Bojic S, et al. (2017) An iPSC Patient Specific Model of CFH (Y402H) Polymorphism Displays Characteristic Features of AMD and Indicates a Beneficial Role for UV Light Exposure. Stem Cells (Dayton, Ohio)
Brown A, Patel S, Ward C, et al. (2016) PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Scientific Reports. 6: 31750
Hewitt G, Carroll B, Sarallah R, et al. (2016) SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 0
Ward C, Martinez-Lopez N, Otten EG, et al. (2016) Autophagy, lipophagy and lysosomal lipid storage disorders. Biochimica Et Biophysica Acta
Dalle Pezze P, Nelson G, Otten EG, et al. (2014) Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions. Plos Computational Biology. 10: e1003728
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