Daniel O'Reilly
Affiliations: | RNA Therapeutics Institute, University of Massachusetts Medical School |
Area:
oligonucleotide synthesis, chemical modification and translational biologyGoogle:
"Daniel O'Reilly"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Masad J. Damha | grad student | 2014-2019 | McGill |
| Anastasia Khvorova | post-doc | 2020- | University of Massachusetts Medical School, USA (Neurotree) |
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Publications
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| Engelbeen S, O'Reilly D, Van De Vijver D, et al. (2023) Challenges of Assessing Exon 53 Skipping of the Human Transcript with Locked Nucleic Acid-Modified Antisense Oligonucleotides in a Mouse Model for Duchenne Muscular Dystrophy. Nucleic Acid Therapeutics. 33: 348-360 |
| O'Reilly D, Belgrad J, Ferguson C, et al. (2023) Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| O'Reilly D, Belgrad J, Ferguson C, et al. (2023) Di-valent siRNA Mediated Silencing of MSH3 Blocks Somatic Repeat Expansion in Mouse Models of Huntington's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Hariharan VN, Shin M, Chang CW, et al. (2023) Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219523120 |
| Buijsen RAM, Lacroix A, Ochaba J, et al. (2022) 17th Annual Meeting of the Oligonucleotide Therapeutics Society: A Tribute to Bob Letsinger, Progress in = 1 Treatments, and Successful First In-Humans CRISPR Trials. Nucleic Acid Therapeutics. 32: 1-7 |
| Ageely EA, Chilamkurthy R, Jana S, et al. (2021) Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles. Nature Communications. 12: 6591 |
| Barkau CL, O'Reilly D, Eddington SB, et al. (2021) Small Nucleic Acids and the Path to the Clinic for Anti-CRISPR. Biochemical Pharmacology. 114492 |
| Thorpe JD, O'Reilly D, Friscic T, et al. (2020) Mechanochemical synthesis of short DNA fragments. Chemistry (Weinheim An Der Bergstrasse, Germany) |
| Barkau CL, O'Reilly D, Rohilla KJ, et al. (2019) Rationally Designed Small Nucleic Acid-Based Inhibitors of CRISPR-Cas9. Nucleic Acid Therapeutics |
| Debacker AJ, Sharma VK, Meda Krishnamurthy P, et al. (2018) Next-generation PNA chimeras exhibit high affinity and potent gene silencing. Biochemistry |