Daniel Allen Osborne
Affiliations: | University of Portland, Portland, OR, United States |
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Parents
Sign in to add mentorAbby L. Parrill | grad student | University of Memphis | |
Edward J. Valente | grad student | Mississippi College |
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Publications
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Valentine WJ, Godwin VI, Osborne DA, et al. (2011) FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain 2. The Journal of Biological Chemistry. 286: 30513-25 |
North EJ, Osborne DA, Bridson PK, et al. (2009) Autotaxin structure-activity relationships revealed through lysophosphatidylcholine analogs. Bioorganic & Medicinal Chemistry. 17: 3433-42 |
Fells JI, Tsukahara R, Fujiwara Y, et al. (2008) Identification of non-lipid LPA3 antagonists by virtual screening. Bioorganic & Medicinal Chemistry. 16: 6207-17 |
Pham TC, Fells JI, Osborne DA, et al. (2008) Molecular recognition in the sphingosine 1-phosphate receptor family. Journal of Molecular Graphics & Modelling. 26: 1189-201 |
Fujiwara Y, Osborne DA, Walker MD, et al. (2007) Identification of the hydrophobic ligand binding pocket of the S1P1 receptor. The Journal of Biological Chemistry. 282: 2374-85 |
Jo E, Sanna MG, Gonzalez-Cabrera PJ, et al. (2005) S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chemistry & Biology. 12: 703-15 |
Inagaki Y, Pham TT, Fujiwara Y, et al. (2005) Sphingosine 1-phosphate analogue recognition and selectivity at S1P4 within the endothelial differentiation gene family of receptors. The Biochemical Journal. 389: 187-95 |
Holdsworth G, Osborne DA, Pham TT, et al. (2004) A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor. Bmc Biochemistry. 5: 12 |
Osborne DA, Dreher WR, Gore HR, et al. (2000) Racemic and (+)-ethyl 2-acetamido-2-carboxy-5-oxohexanoate Journal of Chemical Crystallography. 30: 583-588 |