Stephan N. Witt, Ph.D.

Affiliations: 
1993- Biochemistry & Molecular Biology Louisiana State University Health Sciences Center - Shreveport 
Area:
alpha-synuclein, amyloid, melanoma, neurodegeneration, Parkinson's disease, vesicular trafficking
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"Stephan Witt"
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Arnold MR, Cohn GM, Oxe KC, et al. (2024) Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma. Biorxiv : the Preprint Server For Biology
Gajendran N, Rajasekaran S, Witt SN. (2023) Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility. Scientific Reports. 13: 9243
Rajasekaran S, Patel D, Witt SN. (2022) α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo. Biochemical and Biophysical Research Communications. 603: 7-12
Rajasekaran S, Peterson PP, Liu Z, et al. (2021) α-Synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae. Human Molecular Genetics
Shekoohi S, Rajasekaran S, Patel D, et al. (2021) Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth. Scientific Reports. 11: 5267
Patel D, Witt SN. (2018) Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting. Journal of Experimental Neuroscience. 12: 1179069518796215
Patel D, Xu C, Nagarajan S, et al. (2018) Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson's disease. Human Molecular Genetics
Patel D, Witt SN. (2017) Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease. Oxidative Medicine and Cellular Longevity. 2017: 4829180
Wang S, Zhang S, Xu C, et al. (2016) Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease. Plos One. 11: e0164465
Liu X, Lee YJ, Liou LC, et al. (2011) Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast. Human Molecular Genetics. 20: 3401-14
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