Amanda L. Wolfe, Ph.D.
Affiliations: | Chemistry | UNC Asheville |
Area:
Medicinal Chemistry, Organic synthesisWebsite:
https://chemistry.unca.edu/faces/faculty/wolfeGoogle:
"Amanda Wolfe"Mean distance: 8.34 | S | N | B | C | P |
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Publications
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| Bouthillette LM, Darcey CA, Handy TE, et al. (2017) Isolation of the antibiotic pseudopyronine B and SAR evaluation of C3/C6 alkyl analogs. Bioorganic & Medicinal Chemistry Letters |
| Wolfe AL, Duncan KK, Lajiness JP, et al. (2013) A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding. Journal of Medicinal Chemistry. 56: 6845-57 |
| Vielhauer GA, Swink M, Parelkar NK, et al. (2013) Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers. Cancer Biology & Therapy. 14: 527-36 |
| Wolfe AL, Duncan KK, Parelkar NK, et al. (2013) Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs. Journal of Medicinal Chemistry. 56: 4104-15 |
| Xie J, Wolfe AL, Boger DL. (2013) Total synthesis of kopsinine. Organic Letters. 15: 868-70 |
| Xie J, Wolfe AL, Boger DL. (2013) ChemInform Abstract: Total Synthesis of Kopsinine (I). Cheminform. 44: no-no |
| Wolfe AL, Duncan KK, Parelkar NK, et al. (2012) A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct. Journal of Medicinal Chemistry. 55: 5878-86 |
| Ballard TE, Richards JJ, Wolfe AL, et al. (2008) Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10745-61 |
| Mammana A, Asakawa T, Bitsch-Jensen K, et al. (2008) Synthesis and characterization of water-soluble free-base, zinc and copper porphyrin-oligonucleotide conjugates. Bioorganic & Medicinal Chemistry. 16: 6544-51 |