Hong C. Shen, Ph.D.
Affiliations: | Med. Chem. | Roche, Indianapolis, IN, United States |
Area:
Drug discoveryGoogle:
"Hong Shen"Bio:
http://searchworks.stanford.edu/view/5584165
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Mean distance: 7.64
Parents
Sign in to add mentor| Richard P. Hsung | research assistant | UMN | ||
| Barry M. Trost | grad student | 2003 | Stanford | |
| (The impact of palladium and ruthenium methodologies on strategies for the total syntheses of natural products) | ||||
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Publications
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| Paudyal MP, Wang M, Siitonen JH, et al. (2021) Intramolecular N-Me and N-H aminoetherification for the synthesis of -unprotected 3-amino-O-heterocycles. Organic & Biomolecular Chemistry |
| Hu Y, Shi H, Zhou M, et al. (2020) Discovery of Pyrido[2,3-b]indole Derivatives with Gram-negative Activity Targeting Both DNA Gyrase and Topoisomerase IV. Journal of Medicinal Chemistry |
| Liu Y, Wu J, Zhou M, et al. (2020) Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors. Journal of Medicinal Chemistry |
| Wang D, Liu Y, Zhu W, et al. (2020) Efficient Synthesis of Substituted Morpholine Derivatives via an Indium(III)-catalyzed Reductive Etherification Reaction Chemistry Letters. 49: 709-712 |
| Wu J, Zhang H, Ding X, et al. (2020) Efficient synthesis of perfluoroalkylated quinolines via a metal-free cascade Michael addition/intramolecular rearrangement cyclization process Tetrahedron. 76: 131518 |
| Zheng X, Liang C, Wang L, et al. (2019) Discovery of (aza)indole derivatives as novel respiratory syncytial virus fusion inhibitors. Medchemcomm. 10: 970-973 |
| Wu J, Zhang H, Ding X, et al. (2019) Facile synthesis of fluoroalkylated quinolones using fluoroalk-2-ynoates as fluorinated building blocks Journal of Fluorine Chemistry. 220: 54-60 |
| Zheng X, Liang C, Wang L, et al. (2018) Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally Bioavailable Respiratory Syncytial Virus Fusion Inhibitors. Journal of Medicinal Chemistry |
| Wu J, Zhang H, Ding X, et al. (2018) Potassium iodide promoted one-pot synthesis of fluoroalkylated quinoxalines via a tandem Michael addition / azidation / cycloamination approach. The Journal of Organic Chemistry |
| Zhou M, Tan X, Hu Y, et al. (2018) Highly Chemo- and Regioselective Vinylation of N-Heteroarenes with Vinylsulfonium Salts. The Journal of Organic Chemistry |