Juan Pablo Maianti
Affiliations: | Chemistry | Harvard University, Cambridge, MA, United States |
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Parents
Sign in to add mentor| Stephen Hanessian | grad student | Université de Montréal | |
| David R. Liu | grad student | Harvard |
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| Usanov DL, Chan AI, Maianti JP, et al. (2019) Author Correction: Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nature Chemistry |
| Maianti JP, Tan GA, Vetere A, et al. (2019) Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nature Chemical Biology |
| Koblan LW, Doman JL, Wilson C, et al. (2018) Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nature Biotechnology |
| Kanazawa H, Saavedra OM, Maianti JP, et al. (2018) Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside. Chemmedchem |
| Usanov DL, Chan AI, Maianti JP, et al. (2018) Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nature Chemistry |
| Maianti JP, Hanessian S. (2016) Structural hybridization of three aminoglycoside antibiotics yields a potent broad-spectrum bactericide that eludes bacterial resistance enzymes Medchemcomm. 7: 170-176 |
| Maianti JP, Kanazawa H, Dozzo P, et al. (2014) Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs. Acs Chemical Biology. 9: 2067-73 |
| Maianti JP, McFedries A, Foda ZH, et al. (2014) Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 511: 94-8 |
| Hanessian S, Saavedra OM, Vilchis-Reyes MA, et al. (2014) Synthesis, broad spectrum antibacterial activity, and X-ray co-crystal structure of the decoding bacterial ribosomal A-site with 4′-deoxy-4′-fluoro neomycin analogs Chemical Science. 5: 4621-4632 |
| Kondo J, Koganei M, Maianti JP, et al. (2013) Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites. Chemmedchem. 8: 733-9 |