Jonathan David Gough

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1998-2004 Chemistry Syracuse University, Syracuse, NY, United States 
Website:
https://www.proquest.com/docview/305089204/
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Watson James Lees grad student 1998-2004 Syracuse
 (Aromatic thiol based redox buffers: Increasing the folding rates of disulfide containing proteins.)
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Gough JD, Barrett EJ, Silva Y, et al. (2006) ortho- and meta-substituted aromatic thiols are efficient redox buffers that increase the folding rate of a disulfide-containing protein. Journal of Biotechnology. 125: 39-47
Gough JD, Lees WJ. (2005) Increased catalytic activity of protein disulfide isomerase using aromatic thiol based redox buffers. Bioorganic & Medicinal Chemistry Letters. 15: 777-81
Gough JD, Lees WJ. (2005) Effects of redox buffer properties on the folding of a disulfide-containing protein: dependence upon pH, thiol pKa, and thiol concentration. Journal of Biotechnology. 115: 279-90
Gough JD, Gargano JM, Donofrio AE, et al. (2003) Aromatic thiol pKa effects on the folding rate of a disulfide containing protein. Biochemistry. 42: 11787-97
Gough JD, Williams RH, Donofrio AE, et al. (2002) Folding disulfide-containing proteins faster with an aromatic thiol. Journal of the American Chemical Society. 124: 3885-92
Musa H, Gough JD, Lees WJ, et al. (2001) Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ions. Biophysical Journal. 81: 3253-74
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